Enhancing mesenchymal stem cell response using uniaxially stretched poly(ε-caprolactone) film micropatterns for vascular tissue engineering application

• Main Authors: Wang, Zu-yong, Teoh, Swee Hin, Johana, Nuryanti Binti, Khoon Chong, Mark Seow, Teo, Erin Yiling, Hong, Ming-hui, Yen Chan, Jerry Kok, San Thian, Eng
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Medicine::Tissue engineering
• Online Access: https://hdl.handle.net/10356/96200; http://hdl.handle.net/10220/38470
• Institution: Nanyang Technological University

Regeneration of tunica media with anisotropic architecture still remains a challenging issue for vascular tissue engineering (TE). Herein, we present the development of flexible poly(ε-caprolactone) (PCL) film micropatterns to regulate mesenchymal stem cells (MSCs) function for tunica media construc...