Prediction of trans-regulators of recombination hotspots in mouse genome

• المؤلفون الرئيسيون: Przytycka, Teresa M., Wu, Min, Kwoh, Chee Keong, Li, Jing, Zheng, Jie
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: Conference or Workshop Item
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science::Medicine::Biomedical engineering
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/96527; http://hdl.handle.net/10220/17350

The regulatory mechanism of recombination is a fundamental problem in genomics, with wide applications in genome wide association studies, birth-defect diseases, molecular evolution, cancer research, etc. In mammalian genomes, recombination events cluster into short genomic regions called "reco...