Predicting DNA sequence motifs of recombination hotspots by integrative visualization and analysis

• Main Authors: Khil, Pavel P., Przytycka, Teresa M., Yang, Peng, Wu, Min, Kwoh, Chee Keong, R. Daniel Camerini-Otero, Zheng, Jie
• Other Authors: School of Computer Engineering
• Format: Conference or Workshop Item
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Computer science and engineering::Software
• Online Access: https://hdl.handle.net/10356/83920; http://hdl.handle.net/10220/18173
• Institution: Nanyang Technological University

Meiotic recombination hotspots play important roles in life sciences, but the regulatory mechanism remain unclear. To predict DNA sequence motifs that regulate recombination hotspots, we designed an open source software tool called “LDsplit” that detects SNPs (single nucleotide polymorphisms) assoc...