Predicting DNA sequence motifs of recombination hotspots by integrative visualization and analysis

• المؤلفون الرئيسيون: Khil, Pavel P., Przytycka, Teresa M., Yang, Peng, Wu, Min, Kwoh, Chee Keong, R. Daniel Camerini-Otero, Zheng, Jie
• مؤلفون آخرون: School of Computer Engineering
• التنسيق: Conference or Workshop Item
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Engineering::Computer science and engineering::Software
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83920; http://hdl.handle.net/10220/18173
• المؤسسة: Nanyang Technological University

Meiotic recombination hotspots play important roles in life sciences, but the regulatory mechanism remain unclear. To predict DNA sequence motifs that regulate recombination hotspots, we designed an open source software tool called “LDsplit” that detects SNPs (single nucleotide polymorphisms) assoc...