Epigenetic functions enriched in transcription factors binding to mouse recombination hotspots

• Main Authors: Wu, Min, Kwoh, Chee Keong, Przytycka, Teresa M., Li, Jing, Zheng, Jie
• 其他作者: School of Computer Engineering
• 格式: Article
• 語言: English
• 出版: 2013
• 主題: DRNTU::Engineering::Computer science and engineering
• 在線閱讀: https://hdl.handle.net/10356/100939; http://hdl.handle.net/10220/18190

The regulatory mechanism of recombination is a fundamental problem in genomics, with wide applications in genome-wide association studies, birth-defect diseases, molecular evolution, cancer research, etc. In mammalian genomes, recombination events cluster into short genomic regions called “recombina...