Epigenetic functions enriched in transcription factors binding to mouse recombination hotspots

• Main Authors: Wu, Min, Kwoh, Chee Keong, Przytycka, Teresa M., Li, Jing, Zheng, Jie
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Computer science and engineering
• Online Access: https://hdl.handle.net/10356/100939; http://hdl.handle.net/10220/18190
• Institution: Nanyang Technological University

The regulatory mechanism of recombination is a fundamental problem in genomics, with wide applications in genome-wide association studies, birth-defect diseases, molecular evolution, cancer research, etc. In mammalian genomes, recombination events cluster into short genomic regions called “recombina...