Prediction of trans-regulators of recombination hotspots in mouse genome

• Main Authors: Przytycka, Teresa M., Wu, Min, Kwoh, Chee Keong, Li, Jing, Zheng, Jie
• 其他作者: School of Chemical and Biomedical Engineering
• 格式: Conference or Workshop Item
• 語言: English
• 出版: 2013
• 主題: DRNTU::Science::Medicine::Biomedical engineering
• 在線閱讀: https://hdl.handle.net/10356/96527; http://hdl.handle.net/10220/17350
• 機構: Nanyang Technological University

The regulatory mechanism of recombination is a fundamental problem in genomics, with wide applications in genome wide association studies, birth-defect diseases, molecular evolution, cancer research, etc. In mammalian genomes, recombination events cluster into short genomic regions called "reco...