Nanofiber-mediated controlled release of siRNA complexes for long term gene-silencing applications

• المؤلفون الرئيسيون: Rujitanaroj, Pim-On, Wang, Yu-Cai, Wang, Jun, Chew, Sing Yian
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science::Medicine::Biomedical engineering
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/96598; http://hdl.handle.net/10220/9974
• المؤسسة: Nanyang Technological University

Nanofiber scaffold-mediated delivery of small-interfering RNA (siRNA) holds great potential in regenerative medicine by providing biomimicking topographical signals and enhanced gene silencing effects to seeded cells. While the delivery of naked siRNA was demonstrated previously using poly (ε-caprol...