High-resolution crystal structure of FKBP12 from Aedes aegypti

• Main Authors: Rajan, Sreekanth, Saw, Kai Qian, Nguyen, Quoc Toan, Baek, Kwanghee, Yoon, Ho Sup
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/97150; http://hdl.handle.net/10220/10490
• Institution: Nanyang Technological University

Dengue is one of the most infectious viral diseases prevalent mainly in tropical countries. The virus is transmitted by Aedes species of mosquito, primarily Aedes aegypti. Dengue remains a challenging drug target for years as the virus eludes the immune responses. Currently, no vaccines or antiviral...