Access to spirocyclic oxindoles via N-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines

Access to spirocyclic oxindoles via N-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines

A diastereoselective access to β-lactam fused spirocyclic oxindoles and related compounds bearing all carbon spiro centers is described. This N-heterocyclic carbene-catalyzed process employed challenging β,β-disubstituted α,β-unsaturated imines to react with enals.

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Main Authors: Jiang, Kun, Tiwari, Bhoopendra, Chi, Robin Yonggui
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/97225
http://hdl.handle.net/10220/10640
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-972252020-03-07T12:34:41Z Access to spirocyclic oxindoles via N-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines Jiang, Kun Tiwari, Bhoopendra Chi, Robin Yonggui School of Physical and Mathematical Sciences A diastereoselective access to β-lactam fused spirocyclic oxindoles and related compounds bearing all carbon spiro centers is described. This N-heterocyclic carbene-catalyzed process employed challenging β,β-disubstituted α,β-unsaturated imines to react with enals. 2013-06-25T06:51:41Z 2019-12-06T19:40:22Z 2013-06-25T06:51:41Z 2019-12-06T19:40:22Z 2012 2012 Journal Article Jiang, K., Tiwari, B., & Chi, Y. R. (2012). Access to Spirocyclic Oxindoles via N-Heterocyclic Carbene-Catalyzed Reactions of Enals and Oxindole-Derived α,β-Unsaturated Imines. Organic Letters, 14(9), 2382-2385. 1523-7060 https://hdl.handle.net/10356/97225 http://hdl.handle.net/10220/10640 10.1021/ol3008028 173623 en Organic letters © 2012 American Chemical Society.
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
description A diastereoselective access to β-lactam fused spirocyclic oxindoles and related compounds bearing all carbon spiro centers is described. This N-heterocyclic carbene-catalyzed process employed challenging β,β-disubstituted α,β-unsaturated imines to react with enals.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Jiang, Kun
Tiwari, Bhoopendra
Chi, Robin Yonggui
format Article
author Jiang, Kun
Tiwari, Bhoopendra
Chi, Robin Yonggui
spellingShingle Jiang, Kun
Tiwari, Bhoopendra
Chi, Robin Yonggui
Access to spirocyclic oxindoles via N-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines
author_sort Jiang, Kun
title Access to spirocyclic oxindoles via N-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines
title_short Access to spirocyclic oxindoles via N-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines
title_full Access to spirocyclic oxindoles via N-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines
title_fullStr Access to spirocyclic oxindoles via N-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines
title_full_unstemmed Access to spirocyclic oxindoles via N-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines
title_sort access to spirocyclic oxindoles via n-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines
publishDate 2013
url https://hdl.handle.net/10356/97225
http://hdl.handle.net/10220/10640
_version_ 1681049246918246400

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