Structural basis of RNA binding by leucine zipper GCN4

• Main Authors: Nikolaev, Yaroslav, Pervushin, Konstantin
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/97237; http://hdl.handle.net/10220/10556
• Institution: Nanyang Technological University

Recently, we showed that leucine zipper (LZ) motifs of basic leucine zipper (bZIP) transcription factors GCN4 and c-Jun are capable of catalyzing degradation of RNA (Nikolaev et al., PLoS ONE 2010; 5:e10765). This observation is intriguing given the tight regulation of RNA turnover control and the a...