Selective catalytic sp3 C–O bond cleavage with C–N bond formation in 3-alkoxy-1-propanols
The ruthenium catalyzed selective sp3 C–O cleavage with amide formation was reported in reactions of 3-alkoxy-1-propanol derivatives and amines. The cleavage only occurs at the C3–O position even with 3-benzyloxy-1-propanol. Based on the experimental results, O-bound and C-bound Ru enolate complexes...
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sg-ntu-dr.10356-973602020-03-07T12:34:43Z Selective catalytic sp3 C–O bond cleavage with C–N bond formation in 3-alkoxy-1-propanols Chen, Cheng Hong, Soon Hyeok School of Physical and Mathematical Sciences The ruthenium catalyzed selective sp3 C–O cleavage with amide formation was reported in reactions of 3-alkoxy-1-propanol derivatives and amines. The cleavage only occurs at the C3–O position even with 3-benzyloxy-1-propanol. Based on the experimental results, O-bound and C-bound Ru enolate complexes were proposed as key intermediates for the unique selective sp3 C–O bond cleavage in 3-alkoxy-1-propanols. 2013-06-25T03:59:02Z 2019-12-06T19:41:51Z 2013-06-25T03:59:02Z 2019-12-06T19:41:51Z 2012 2012 Journal Article Chen, C., & Hong, S. H. (2012). Selective Catalytic sp3 C–O Bond Cleavage with C–N Bond Formation in 3-Alkoxy-1-propanols. Organic Letters, 14(12), 2992-2995. 1523-7060 https://hdl.handle.net/10356/97360 http://hdl.handle.net/10220/10607 10.1021/ol3009842 en Organic letters © 2012 American Chemical Society. |
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The ruthenium catalyzed selective sp3 C–O cleavage with amide formation was reported in reactions of 3-alkoxy-1-propanol derivatives and amines. The cleavage only occurs at the C3–O position even with 3-benzyloxy-1-propanol. Based on the experimental results, O-bound and C-bound Ru enolate complexes were proposed as key intermediates for the unique selective sp3 C–O bond cleavage in 3-alkoxy-1-propanols. |
| author2 |
School of Physical and Mathematical Sciences |
| author_facet |
School of Physical and Mathematical Sciences Chen, Cheng Hong, Soon Hyeok |
| format |
Article |
| author |
Chen, Cheng Hong, Soon Hyeok |
| spellingShingle |
Chen, Cheng Hong, Soon Hyeok Selective catalytic sp3 C–O bond cleavage with C–N bond formation in 3-alkoxy-1-propanols |
| author_sort |
Chen, Cheng |
| title |
Selective catalytic sp3 C–O bond cleavage with C–N bond formation in 3-alkoxy-1-propanols |
| title_short |
Selective catalytic sp3 C–O bond cleavage with C–N bond formation in 3-alkoxy-1-propanols |
| title_full |
Selective catalytic sp3 C–O bond cleavage with C–N bond formation in 3-alkoxy-1-propanols |
| title_fullStr |
Selective catalytic sp3 C–O bond cleavage with C–N bond formation in 3-alkoxy-1-propanols |
| title_full_unstemmed |
Selective catalytic sp3 C–O bond cleavage with C–N bond formation in 3-alkoxy-1-propanols |
| title_sort |
selective catalytic sp3 c–o bond cleavage with c–n bond formation in 3-alkoxy-1-propanols |
| publishDate |
2013 |
| url |
https://hdl.handle.net/10356/97360 http://hdl.handle.net/10220/10607 |
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1681049385312452608 |