Mutations I117V and I117M and Oseltamivir sensitivity of pandemic (H1N1) 2009 viruses
Analysis of mutations I117V and I117M in the neuraminidase of influenza A pandemic (H1N1) 2009 viruses showed that I117V confers a mild reduction in oseltamivir sensitivity and has a synergistic effect of further increasing resistance when combined with H275Y. Contrary to recent reports, the I117M m...
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Main Authors: | Hurt, Aeron, Leang, Sook, Speers, David, Barr, Ian G., Maurer-Stroh, Sebastian |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2013
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/98120 http://hdl.handle.net/10220/13278 |
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Institution: | Nanyang Technological University |
Language: | English |
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