Mild and efficient C2-alkenylation of indoles with alkynes catalyzed by a cobalt complex

• المؤلفون الرئيسيون: Ding, Zhenhua, Yoshikai, Naohiko
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science::Chemistry
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/98454; http://hdl.handle.net/10220/12470
• المؤسسة: Nanyang Technological University

Direct alkenylation of the C2-position of indoles bearing an easily removable N-pyrimidyl group with alkynes has been achieved by using a cobalt catalyst complexed with a phosphine–pyridine bidentate ligand. This reaction has wide substrate scope and is highly efficient and stereoselective at room t...