Globalized bipartite local model for drug-target interaction prediction

• Main Authors: Mei, Jian-Ping, Kwoh, Chee Keong, Yang, Peng, Li, Xiaoli, Zheng, Jie
• Other Authors: School of Computer Engineering
• Format: Conference or Workshop Item
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/98786; http://hdl.handle.net/10220/12583
• Institution: Nanyang Technological University

In pharmacology, it is essential to identify the interactions between drug and targets to understand its effects. Supervised learning with Bipartite Local Model (BLM) recently has been shown to be effective for prediction of drug-target interactions by first predicting target proteins of a given kno...