Structure, activity and interactions of the cysteine deleted analog of tachyplesin-1 with lipopolysaccharide micelle : mechanistic insights into outer-membrane permeabilization and endotoxin neutralization
Tachyplesin-1, a disulfide stabilized β-hairpin antimicrobial peptide, can be found at the hemocytes of horse shoe crab Tachypleus tridentatus. A cysteine deleted linear analog of tachyplesin-1 or CDT (KWFRVYRGIYRRR-NH2) contains a broad spectrum of bactericidal activity with a reduced hemolytic pro...
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Main Authors: | Saravanan, Rathi, Mohanram, Harini, Joshi, Mangesh, Torres, Jaume, Ruedl, Christiane, Bhattacharjya, Surajit, Domadia, Prerna N. |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2013
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/98894 http://hdl.handle.net/10220/12689 |
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Institution: | Nanyang Technological University |
Language: | English |
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