Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes
Class I Major Histocompatibility Complex (MHC) molecules evolved to sample degraded protein fragments from the interior of the cell, and to display them at the surface for immune surveillance by CD8+ T cells. The ability of these lymphocytes to identify immunogenic peptide-MHC (pMHC) products on, fo...
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Main Authors: | Low, Jianrong L., Gehring, Adam J., Kranz, David M., Grotenbreg, Gijsbert M., Yau, Yin Hoe, Shochat, Susana Geifman, Bertoletti, Antonio, Naidoo, Anneta, Yeo, Gladys, Ho, Zi Zong |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2013
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/98967 http://hdl.handle.net/10220/10919 |
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Institution: | Nanyang Technological University |
Language: | English |
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