Arene CH=O hydrogen bonding : a stereocontrolling tool in palladium-catalyzed arylation and vinylation of ketones

• Main Authors: Huang, Zhiyan, Lim, Li Hui, Chen, Zuliang, Li, Yongxin, Zhou, Feng, Su, Haibin, Zhou, Jianrong Steve
• 其他作者: School of Materials Science & Engineering
• 格式: Article
• 語言: English
• 出版: 2013
• 在線閱讀: https://hdl.handle.net/10356/99248; http://hdl.handle.net/10220/17600
• 機構: Nanyang Technological University

Weak is powerful: For the arylation of tin enolates, the palladium catalyst engages in weak CH=O hydrogen bonds to control stereoselectivity (see scheme). Similar catalysts capable of NH=O hydrogen bonding also works well.