Monomer-dimer equilibrium for the 5′-5′ stacking of propeller-type parallel-stranded G-quadruplexes : NMR structural study

• Main Authors: Do, Ngoc Quang, Phan, Anh Tuân
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/99416; http://hdl.handle.net/10220/12935
• Institution: Nanyang Technological University

Guanine-rich sequence motifs, which contain tracts of three consecutive guanines connected by single non-guanine nucleotides, are abundant in the human genome and can form a robust G-quadruplex structure with high stability. Herein, by using NMR spectroscopy, we investigate the equilibrium between m...