In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles

• Main Authors: Wang, Chao, Teng, Xue, Cheng, Kai, Cheng, Zhen, Huang, Ling, Liu, Zhuang, Liu, Xiaogang, Xing, Bengang, Yang, Yanmei, Shao, Qing, Deng, Renren
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/99542; http://hdl.handle.net/10220/12461
• Institution: Nanyang Technological University

Trading up: A bioimaging system that is based on caged D-luciferin/upconversion nanoparticle conjugate has been developed. The nanoparticles upconvert near-infrared light into UV light, which triggers the photorelease of D-luciferin (see scheme) and leads to enhanced fluorescence and bioluminescence...