A Pt(II)-dip complex stabilizes parallel c-myc G-quadruplex

A new G-quadruplex (GQ) stabilizer, [Pt(Dip)2](PF6)2 (Dip: 4,7-diphenyl-1,10-phenanthroline), is prepared by the microwave irradiation method. The complex can highly stabilize G-quadruplex, but has negligible interactions with duplex DNA. Aromatic anchors on the polypyridyl ligands bestow the stabil...

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Bibliographic Details
Main Authors: Wang, Jintao, Lu, Kaihui, Xuan, Shuguang, Toh, Zaozhen, Zhang, Dawei, Shao, Fangwei
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/99688
http://hdl.handle.net/10220/9988
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Institution: Nanyang Technological University
Language: English