Dual functional dinuclear platinum complex with selective reactivity towards c-myc G-quadruplex
G-quadruplexes (GQ) folded by the oncogenic G-rich sequences are the promising targets for developing anticancer therapeutic molecules. However, the current drug development mainly focused on non-covalent dynamic binders to stabilize GQ structures, while the covalent targeting from inorganic complex...
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Main Authors: | , , , |
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格式: | Article |
語言: | English |
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2018
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在線閱讀: | https://hdl.handle.net/10356/87503 http://hdl.handle.net/10220/45427 |
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機構: | Nanyang Technological University |
語言: | English |