Dual functional dinuclear platinum complex with selective reactivity towards c-myc G-quadruplex
G-quadruplexes (GQ) folded by the oncogenic G-rich sequences are the promising targets for developing anticancer therapeutic molecules. However, the current drug development mainly focused on non-covalent dynamic binders to stabilize GQ structures, while the covalent targeting from inorganic complex...
Saved in:
Main Authors: | He, Lei, Meng, Zhenyu, Xu, Dechen, Shao, Fangwei |
---|---|
Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2018
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/87503 http://hdl.handle.net/10220/45427 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Aza-bridged bisphenanthrolinyl Pt(ii) complexes : efficient stabilization and topological selectivity on telomeric G-quadruplexes
by: He, Lei, et al.
Published: (2018) -
Studies of new properties and applications of G-quadruplex DNA
by: NG TAO TAO MAGDELINE
Published: (2011) -
Effects of LNA modification on the stability and structure of DNA G-quadruplex
by: Li, Zhe
Published: (2013) -
Stapling a G-quadruplex specific peptide
by: Yaneva, Militsa Yavorova, et al.
Published: (2020) -
Non-Canonical G-quadruplexes cause the hCEB1 minisatellite instability in Saccharomyces cerevisiae
by: Piazza, Aurèle, et al.
Published: (2017)