Dual functional dinuclear platinum complex with selective reactivity towards c-myc G-quadruplex

G-quadruplexes (GQ) folded by the oncogenic G-rich sequences are the promising targets for developing anticancer therapeutic molecules. However, the current drug development mainly focused on non-covalent dynamic binders to stabilize GQ structures, while the covalent targeting from inorganic complex...

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Bibliographic Details
Main Authors: He, Lei, Meng, Zhenyu, Xu, Dechen, Shao, Fangwei
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87503
http://hdl.handle.net/10220/45427
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Institution: Nanyang Technological University
Language: English
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