Development of HIV-1 fusion inhibitors targeting gp41

• Main Authors: Lu, K., Asyifah, M. R., Shao, F., Zhang, D.
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Medicine::Biomedical engineering
• Online Access: https://hdl.handle.net/10356/99957; http://hdl.handle.net/10220/19663
• Institution: Nanyang Technological University

The HIV-1 envelope protein glycoprotein 41 (gp41) is crucial in the HIV-1 infection process, therefore gp41 has emerged as an attractive target for drug design against AIDS. During the past few decades, tremendous efforts have been made on developing inhibitors that can prevent the HIV-1 entry proce...