Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach: An alternative tool to discriminate between the human adenosine A2A and A3 receptor pyrazolo-triazolo-pyrimidine antagonists binding sites
10.1016/j.bmc.2009.05.038
Saved in:
Main Authors: | Michielan, L., Bolcato, C., Federico, S., Cacciari, B., Bacilieri, M., Klotz, K.-N., Kachler, S., Pastorin, G., Cardin, R., Sperduti, A., Spalluto, G., Moro, S. |
---|---|
Other Authors: | PHARMACY |
Format: | Article |
Published: |
2014
|
Subjects: | |
Online Access: | http://scholarbank.nus.edu.sg/handle/10635/105748 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | National University of Singapore |
Similar Items
-
Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo- pyrimidines as potent human A3 adenosine receptor antagonists
by: Cheong, S.L., et al.
Published: (2014) -
DESIGN, SYNTHESIS, PHARMACOLOGICAL AND MOLECULAR MODELING EVALUATIONS OF NEW PYRAZOLO-TRIAZOLO-PYRIMIDINE DERIVATIVES AS HUMAN A3 ADENOSINE RECEPTOR ANTAGONISTS
by: CHEONG SIEW LEE
Published: (2011) -
DESIGN, SYNTHESIS, PHARMACOLOGICAL AND MOLECULAR MODELING EVALUATION OF NOVEL PYRAZOLO PYRIMIDINE DERIVATIVES AS HUMAN A3 ADENOSINE RECEPTOR ANTAGONISTS
by: GOPALAKRISHNAN VENKATESAN
Published: (2014) -
Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?
by: Cheong, S.L., et al.
Published: (2014) -
Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand-receptor recognition process
by: Pastorin, G., et al.
Published: (2014)