Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?

10.1016/j.bmc.2011.08.026

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Main Authors:	Cheong, S.L., Dolzhenko, A.V., Paoletta, S., Lee, E.P.R., Kachler, S., Federico, S., Klotz, K.-N., Spalluto, G., Moro, S., Pastorin, G.
Other Authors:	PHARMACY
Format:	Article
Published:	2014
Subjects:	2-Phenyl-pyrazolo-triazolo-pyrimidines Affinity Human A 3 adenosine receptor antagonists Selectivity Structure-affinity relationship
Online Access:	http://scholarbank.nus.edu.sg/handle/10635/105850
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-105850
record_format	dspace
spelling	sg-nus-scholar.10635-1058502023-10-26T21:48:40Z Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors? Cheong, S.L. Dolzhenko, A.V. Paoletta, S. Lee, E.P.R. Kachler, S. Federico, S. Klotz, K.-N. Dolzhenko, A.V. Spalluto, G. Moro, S. Pastorin, G. PHARMACY 2-Phenyl-pyrazolo-triazolo-pyrimidines Affinity Human A 3 adenosine receptor antagonists Selectivity Structure-affinity relationship 10.1016/j.bmc.2011.08.026 Bioorganic and Medicinal Chemistry 19 20 6120-6134 BMECE 2014-10-29T01:51:35Z 2014-10-29T01:51:35Z 2011-10-15 Article Cheong, S.L., Dolzhenko, A.V., Paoletta, S., Lee, E.P.R., Kachler, S., Federico, S., Klotz, K.-N., Dolzhenko, A.V., Spalluto, G., Moro, S., Pastorin, G. (2011-10-15). Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?. Bioorganic and Medicinal Chemistry 19 (20) : 6120-6134. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bmc.2011.08.026 09680896 http://scholarbank.nus.edu.sg/handle/10635/105850 000295494600021 Scopus
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	2-Phenyl-pyrazolo-triazolo-pyrimidines Affinity Human A 3 adenosine receptor antagonists Selectivity Structure-affinity relationship
spellingShingle	2-Phenyl-pyrazolo-triazolo-pyrimidines Affinity Human A 3 adenosine receptor antagonists Selectivity Structure-affinity relationship Cheong, S.L. Dolzhenko, A.V. Paoletta, S. Lee, E.P.R. Kachler, S. Federico, S. Klotz, K.-N. Dolzhenko, A.V. Spalluto, G. Moro, S. Pastorin, G. Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?
description	10.1016/j.bmc.2011.08.026
author2	PHARMACY
author_facet	PHARMACY Cheong, S.L. Dolzhenko, A.V. Paoletta, S. Lee, E.P.R. Kachler, S. Federico, S. Klotz, K.-N. Dolzhenko, A.V. Spalluto, G. Moro, S. Pastorin, G.
format	Article
author	Cheong, S.L. Dolzhenko, A.V. Paoletta, S. Lee, E.P.R. Kachler, S. Federico, S. Klotz, K.-N. Dolzhenko, A.V. Spalluto, G. Moro, S. Pastorin, G.
author_sort	Cheong, S.L.
title	Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?
title_short	Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?
title_full	Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?
title_fullStr	Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?
title_full_unstemmed	Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?
title_sort	does the combination of optimal substitutions at the c 2-, n 5- and n 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human a 3 adenosine receptors?
publishDate	2014
url	http://scholarbank.nus.edu.sg/handle/10635/105850
_version_	1781788125418225664

Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?

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