Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?

Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?

10.1016/j.bmc.2011.08.026

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Bibliographic Details
Main Authors:	Cheong, S.L., Dolzhenko, A.V., Paoletta, S., Lee, E.P.R., Kachler, S., Federico, S., Klotz, K.-N., Spalluto, G., Moro, S., Pastorin, G.
Other Authors:	PHARMACY
Format:	Article
Published:	2014
Subjects:	2-Phenyl-pyrazolo-triazolo-pyrimidines Affinity Human A 3 adenosine receptor antagonists Selectivity Structure-affinity relationship
Online Access:	http://scholarbank.nus.edu.sg/handle/10635/105850
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

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