The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptors antagonists: New insights into structure-affinity relationship and receptor-antagonist recognition
10.1021/jm100049f
Saved in:
Main Authors: | Cheong, S.L., Dolzhenko, A., Kachler, S., Paoletta, S., Federico, S., Cacciari, B., Klotz, K.-N., Moro, S., Spalluto, G., Pastorin, G. |
---|---|
其他作者: | PHARMACY |
格式: | Article |
出版: |
2014
|
在線閱讀: | http://scholarbank.nus.edu.sg/handle/10635/106452 |
標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|
相似書籍
-
Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adenosine receptors?
由: Cheong, S.L., et al.
出版: (2014) -
Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo- pyrimidines as potent human A3 adenosine receptor antagonists
由: Cheong, S.L., et al.
出版: (2014) -
Exploring the directionality of 5-substitutions in a new series of 5-alkylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine as a strategy to design novel human A3 adenosine receptor antagonists
由: Federico, S., et al.
出版: (2014) -
A facile and novel synthesis of N2-, C6-substituted pyrazolo[3,4- d ]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists
由: Venkatesan G., et al.
出版: (2016) -
Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach: An alternative tool to discriminate between the human adenosine A2A and A3 receptor pyrazolo-triazolo-pyrimidine antagonists binding sites
由: Michielan, L., et al.
出版: (2014)