Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
10.1038/ng.2383
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SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH Morris, A.P. Voight, B.F. Teslovich, T.M. Ferreira, T. Segrè, A.V. Steinthorsdottir, V. Strawbridge, R.J. Khan, H. Grallert, H. Mahajan, A. Prokopenko, I. Kang, H.M. Dina, C. Esko, T. Fraser, R.M. Kanoni, S. Kumar, A. Lagou, V. Langenberg, C. Luan, J. Lindgren, C.M. Müller-Nurasyid, M. Pechlivanis, S. Rayner, N.W. Scott, L.J. Wiltshire, S. Yengo, L. Kinnunen, L. Rossin, E.J. Raychaudhuri, S. Johnson, A.D. Dimas, A.S. Loos, R.J.F. Vedantam, S. Chen, H. Florez, J.C. Fox, C. Liu, C.-T. Rybin, D. Couper, D.J. Kao, W.H.L. Li, M. Cornelis, M.C. Kraft, P. Sun, Q. Van Dam, R.M. Stringham, H.M. Chines, P.S. Fischer, K. Fontanillas, P. Holmen, O.L. Hunt, S.E. Jackson, A.U. Kong, A. Lawrence, R. Meyer, J. Perry, J.R.B. Platou, C.G.P. Potter, S. Rehnberg, E. Robertson, N. Sivapalaratnam, S. Stančáková, A. Stirrups, K. Thorleifsson, G. Tikkanen, E. Wood, A.R. Almgren, P. Atalay, M. Benediktsson, R. Bonnycastle, L.L. Burtt, N. Carey, J. Charpentier, G. Crenshaw, A.T. Doney, A.S.F. Dorkhan, M. Edkins, S. Emilsson, V. Eury, E. Forsen, T. Gertow, K. Gigante, B. Grant, G.B. Groves, C.J. Guiducci, C. Herder, C. Hreidarsson, A.B. Hui, J. James, A. Jonsson, A. Rathmann, W. Klopp, N. Kravic, J. Krjutškov, K. Langford, C. Leander, K. Lindholm, E. Lobbens, S. MäNnistö, S. Mirza, G. MüHleisen, T.W. Musk, B. Parkin, M. Rallidis, L. Saramies, J. Sennblad, B. Shah, S. Sigursson, G. Silveira, A. Steinbach, G. Thorand, B. Trakalo, J. Veglia, F. Wennauer, R. Winckler, W. Zabaneh, D. Campbell, H. Van Duijn, C. Uitterlinden, A.G. Hofman, A. Sijbrands, E. Abecasis, G.R. Owen, K.R. Zeggini, E. Trip, M.D. Forouhi, N.G. Syvänen, A.-C. Eriksson, J.G. Peltonen, L. Nöthen, M.M. Balkau, B. Palmer, C.N.A. Lyssenko, V. Tuomi, T. Isomaa, B. Hunter, D.J. Qi, L. Shuldiner, A.R. Roden, M. Barroso, I. Wilsgaard, T. Beilby, J. Hovingh, K. Price, J.F. Wilson, J.F. Rauramaa, R. Lakka, T.A. Lind, L. Dedoussis, G. NjøLstad, I. Pedersen, N.L. Khaw, K.-T. Wareham, N.J. Keinanen-Kiukaanniemi, S.M. Saaristo, T.E. Korpi-HyöVäLti, E. Saltevo, J. Laakso, M. Kuusisto, J. Metspalu, A. Collins, F.S. Mohlke, K.L. Bergman, R.N. Tuomilehto, J. Boehm, B.O. Gieger, C. Hveem, K. Cauchi, S. Froguel, P. Baldassarre, D. Tremoli, E. Humphries, S.E. Saleheen, D. Danesh, J. Ingelsson, E. Ripatti, S. Salomaa, V. Erbel, R. JöCkel, K.-H. Moebus, S. Peters, A. Illig, T. Faire, U.D. Hamsten, A. Morris, A.D. Donnelly, P.J. Frayling, T.M. Hattersley, A.T. Boerwinkle, E. Melander, O. Kathiresan, S. Nilsson, P.M. Deloukas, P. Thorsteinsdottir, U. Groop, L.C. Stefansson, K. Hu, F. Pankow, J.S. Dupuis, J. Meigs, J.B. Altshuler, D. Boehnke, M. McCarthy, M.I. |
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Morris, A.P. Voight, B.F. Teslovich, T.M. Ferreira, T. Segrè, A.V. Steinthorsdottir, V. Strawbridge, R.J. Khan, H. Grallert, H. Mahajan, A. Prokopenko, I. Kang, H.M. Dina, C. Esko, T. Fraser, R.M. Kanoni, S. Kumar, A. Lagou, V. Langenberg, C. Luan, J. Lindgren, C.M. Müller-Nurasyid, M. Pechlivanis, S. Rayner, N.W. Scott, L.J. Wiltshire, S. Yengo, L. Kinnunen, L. Rossin, E.J. Raychaudhuri, S. Johnson, A.D. Dimas, A.S. Loos, R.J.F. Vedantam, S. Chen, H. Florez, J.C. Fox, C. Liu, C.-T. Rybin, D. Couper, D.J. Kao, W.H.L. Li, M. Cornelis, M.C. Kraft, P. Sun, Q. Van Dam, R.M. Stringham, H.M. Chines, P.S. Fischer, K. Fontanillas, P. Holmen, O.L. Hunt, S.E. Jackson, A.U. Kong, A. Lawrence, R. Meyer, J. Perry, J.R.B. Platou, C.G.P. Potter, S. Rehnberg, E. Robertson, N. Sivapalaratnam, S. Stančáková, A. Stirrups, K. Thorleifsson, G. Tikkanen, E. Wood, A.R. Almgren, P. Atalay, M. Benediktsson, R. Bonnycastle, L.L. Burtt, N. Carey, J. Charpentier, G. Crenshaw, A.T. Doney, A.S.F. Dorkhan, M. Edkins, S. Emilsson, V. Eury, E. Forsen, T. Gertow, K. Gigante, B. Grant, G.B. Groves, C.J. Guiducci, C. Herder, C. Hreidarsson, A.B. Hui, J. James, A. Jonsson, A. Rathmann, W. Klopp, N. Kravic, J. Krjutškov, K. Langford, C. Leander, K. Lindholm, E. Lobbens, S. MäNnistö, S. Mirza, G. MüHleisen, T.W. Musk, B. Parkin, M. Rallidis, L. Saramies, J. Sennblad, B. Shah, S. Sigursson, G. Silveira, A. Steinbach, G. Thorand, B. Trakalo, J. Veglia, F. Wennauer, R. Winckler, W. Zabaneh, D. Campbell, H. Van Duijn, C. Uitterlinden, A.G. Hofman, A. Sijbrands, E. Abecasis, G.R. Owen, K.R. Zeggini, E. Trip, M.D. Forouhi, N.G. Syvänen, A.-C. Eriksson, J.G. Peltonen, L. Nöthen, M.M. Balkau, B. Palmer, C.N.A. Lyssenko, V. Tuomi, T. Isomaa, B. Hunter, D.J. Qi, L. Shuldiner, A.R. Roden, M. Barroso, I. Wilsgaard, T. Beilby, J. Hovingh, K. Price, J.F. Wilson, J.F. Rauramaa, R. Lakka, T.A. Lind, L. Dedoussis, G. NjøLstad, I. Pedersen, N.L. Khaw, K.-T. Wareham, N.J. Keinanen-Kiukaanniemi, S.M. Saaristo, T.E. Korpi-HyöVäLti, E. Saltevo, J. Laakso, M. Kuusisto, J. Metspalu, A. Collins, F.S. Mohlke, K.L. Bergman, R.N. Tuomilehto, J. Boehm, B.O. Gieger, C. Hveem, K. Cauchi, S. Froguel, P. Baldassarre, D. Tremoli, E. Humphries, S.E. Saleheen, D. Danesh, J. Ingelsson, E. Ripatti, S. Salomaa, V. Erbel, R. JöCkel, K.-H. Moebus, S. Peters, A. Illig, T. Faire, U.D. Hamsten, A. Morris, A.D. Donnelly, P.J. Frayling, T.M. Hattersley, A.T. Boerwinkle, E. Melander, O. Kathiresan, S. Nilsson, P.M. Deloukas, P. Thorsteinsdottir, U. Groop, L.C. Stefansson, K. Hu, F. Pankow, J.S. Dupuis, J. Meigs, J.B. Altshuler, D. Boehnke, M. McCarthy, M.I. |
spellingShingle |
Morris, A.P. Voight, B.F. Teslovich, T.M. Ferreira, T. Segrè, A.V. Steinthorsdottir, V. Strawbridge, R.J. Khan, H. Grallert, H. Mahajan, A. Prokopenko, I. Kang, H.M. Dina, C. Esko, T. Fraser, R.M. Kanoni, S. Kumar, A. Lagou, V. Langenberg, C. Luan, J. Lindgren, C.M. Müller-Nurasyid, M. Pechlivanis, S. Rayner, N.W. Scott, L.J. Wiltshire, S. Yengo, L. Kinnunen, L. Rossin, E.J. Raychaudhuri, S. Johnson, A.D. Dimas, A.S. Loos, R.J.F. Vedantam, S. Chen, H. Florez, J.C. Fox, C. Liu, C.-T. Rybin, D. Couper, D.J. Kao, W.H.L. Li, M. Cornelis, M.C. Kraft, P. Sun, Q. Van Dam, R.M. Stringham, H.M. Chines, P.S. Fischer, K. Fontanillas, P. Holmen, O.L. Hunt, S.E. Jackson, A.U. Kong, A. Lawrence, R. Meyer, J. Perry, J.R.B. Platou, C.G.P. Potter, S. Rehnberg, E. Robertson, N. Sivapalaratnam, S. Stančáková, A. Stirrups, K. Thorleifsson, G. Tikkanen, E. Wood, A.R. Almgren, P. Atalay, M. Benediktsson, R. Bonnycastle, L.L. Burtt, N. Carey, J. Charpentier, G. Crenshaw, A.T. Doney, A.S.F. Dorkhan, M. Edkins, S. Emilsson, V. Eury, E. Forsen, T. Gertow, K. Gigante, B. Grant, G.B. Groves, C.J. Guiducci, C. Herder, C. Hreidarsson, A.B. Hui, J. James, A. Jonsson, A. Rathmann, W. Klopp, N. Kravic, J. Krjutškov, K. Langford, C. Leander, K. Lindholm, E. Lobbens, S. MäNnistö, S. Mirza, G. MüHleisen, T.W. Musk, B. Parkin, M. Rallidis, L. Saramies, J. Sennblad, B. Shah, S. Sigursson, G. Silveira, A. Steinbach, G. Thorand, B. Trakalo, J. Veglia, F. Wennauer, R. Winckler, W. Zabaneh, D. Campbell, H. Van Duijn, C. Uitterlinden, A.G. Hofman, A. Sijbrands, E. Abecasis, G.R. Owen, K.R. Zeggini, E. Trip, M.D. Forouhi, N.G. Syvänen, A.-C. Eriksson, J.G. Peltonen, L. Nöthen, M.M. Balkau, B. Palmer, C.N.A. Lyssenko, V. Tuomi, T. Isomaa, B. Hunter, D.J. Qi, L. Shuldiner, A.R. Roden, M. Barroso, I. Wilsgaard, T. Beilby, J. Hovingh, K. Price, J.F. Wilson, J.F. Rauramaa, R. Lakka, T.A. Lind, L. Dedoussis, G. NjøLstad, I. Pedersen, N.L. Khaw, K.-T. Wareham, N.J. Keinanen-Kiukaanniemi, S.M. Saaristo, T.E. Korpi-HyöVäLti, E. Saltevo, J. Laakso, M. Kuusisto, J. Metspalu, A. Collins, F.S. Mohlke, K.L. Bergman, R.N. Tuomilehto, J. Boehm, B.O. Gieger, C. Hveem, K. Cauchi, S. Froguel, P. Baldassarre, D. Tremoli, E. Humphries, S.E. Saleheen, D. Danesh, J. Ingelsson, E. Ripatti, S. Salomaa, V. Erbel, R. JöCkel, K.-H. Moebus, S. Peters, A. Illig, T. Faire, U.D. Hamsten, A. Morris, A.D. Donnelly, P.J. Frayling, T.M. Hattersley, A.T. Boerwinkle, E. Melander, O. Kathiresan, S. Nilsson, P.M. Deloukas, P. Thorsteinsdottir, U. Groop, L.C. Stefansson, K. Hu, F. Pankow, J.S. Dupuis, J. Meigs, J.B. Altshuler, D. Boehnke, M. McCarthy, M.I. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes |
author_sort |
Morris, A.P. |
title |
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes |
title_short |
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes |
title_full |
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes |
title_fullStr |
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes |
title_full_unstemmed |
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes |
title_sort |
large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes |
publishDate |
2014 |
url |
http://scholarbank.nus.edu.sg/handle/10635/108768 |
_version_ |
1821181241629605888 |
spelling |
sg-nus-scholar.10635-1087682024-11-13T00:48:36Z Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes Morris, A.P. Voight, B.F. Teslovich, T.M. Ferreira, T. Segrè, A.V. Steinthorsdottir, V. Strawbridge, R.J. Khan, H. Grallert, H. Mahajan, A. Prokopenko, I. Kang, H.M. Dina, C. Esko, T. Fraser, R.M. Kanoni, S. Kumar, A. Lagou, V. Langenberg, C. Luan, J. Lindgren, C.M. Müller-Nurasyid, M. Pechlivanis, S. Rayner, N.W. Scott, L.J. Wiltshire, S. Yengo, L. Kinnunen, L. Rossin, E.J. Raychaudhuri, S. Johnson, A.D. Dimas, A.S. Loos, R.J.F. Vedantam, S. Chen, H. Florez, J.C. Fox, C. Liu, C.-T. Rybin, D. Couper, D.J. Kao, W.H.L. Li, M. Cornelis, M.C. Kraft, P. Sun, Q. Van Dam, R.M. Stringham, H.M. Chines, P.S. Fischer, K. Fontanillas, P. Holmen, O.L. Hunt, S.E. Jackson, A.U. Kong, A. Lawrence, R. Meyer, J. Perry, J.R.B. Platou, C.G.P. Potter, S. Rehnberg, E. Robertson, N. Sivapalaratnam, S. Stančáková, A. Stirrups, K. Thorleifsson, G. Tikkanen, E. Wood, A.R. Almgren, P. Atalay, M. Benediktsson, R. Bonnycastle, L.L. Burtt, N. Carey, J. Charpentier, G. Crenshaw, A.T. Doney, A.S.F. Dorkhan, M. Edkins, S. Emilsson, V. Eury, E. Forsen, T. Gertow, K. Gigante, B. Grant, G.B. Groves, C.J. Guiducci, C. Herder, C. Hreidarsson, A.B. Hui, J. James, A. Jonsson, A. Rathmann, W. Klopp, N. Kravic, J. Krjutškov, K. Langford, C. Leander, K. Lindholm, E. Lobbens, S. MäNnistö, S. Mirza, G. MüHleisen, T.W. Musk, B. Parkin, M. Rallidis, L. Saramies, J. Sennblad, B. Shah, S. Sigursson, G. Silveira, A. Steinbach, G. Thorand, B. Trakalo, J. Veglia, F. Wennauer, R. Winckler, W. Zabaneh, D. Campbell, H. Van Duijn, C. Uitterlinden, A.G. Hofman, A. Sijbrands, E. Abecasis, G.R. Owen, K.R. Zeggini, E. Trip, M.D. Forouhi, N.G. Syvänen, A.-C. Eriksson, J.G. Peltonen, L. Nöthen, M.M. Balkau, B. Palmer, C.N.A. Lyssenko, V. Tuomi, T. Isomaa, B. Hunter, D.J. Qi, L. Shuldiner, A.R. Roden, M. Barroso, I. Wilsgaard, T. Beilby, J. Hovingh, K. Price, J.F. Wilson, J.F. Rauramaa, R. Lakka, T.A. Lind, L. Dedoussis, G. NjøLstad, I. Pedersen, N.L. Khaw, K.-T. Wareham, N.J. Keinanen-Kiukaanniemi, S.M. Saaristo, T.E. Korpi-HyöVäLti, E. Saltevo, J. Laakso, M. Kuusisto, J. Metspalu, A. Collins, F.S. Mohlke, K.L. Bergman, R.N. Tuomilehto, J. Boehm, B.O. Gieger, C. Hveem, K. Cauchi, S. Froguel, P. Baldassarre, D. Tremoli, E. Humphries, S.E. Saleheen, D. Danesh, J. Ingelsson, E. Ripatti, S. Salomaa, V. Erbel, R. JöCkel, K.-H. Moebus, S. Peters, A. Illig, T. Faire, U.D. Hamsten, A. Morris, A.D. Donnelly, P.J. Frayling, T.M. Hattersley, A.T. Boerwinkle, E. Melander, O. Kathiresan, S. Nilsson, P.M. Deloukas, P. Thorsteinsdottir, U. Groop, L.C. Stefansson, K. Hu, F. Pankow, J.S. Dupuis, J. Meigs, J.B. Altshuler, D. Boehnke, M. McCarthy, M.I. SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH 10.1038/ng.2383 Nature Genetics 44 9 981-990 NGENE 2014-11-26T02:12:36Z 2014-11-26T02:12:36Z 2012-09 Article Morris, A.P., Voight, B.F., Teslovich, T.M., Ferreira, T., Segrè, A.V., Steinthorsdottir, V., Strawbridge, R.J., Khan, H., Grallert, H., Mahajan, A., Prokopenko, I., Kang, H.M., Dina, C., Esko, T., Fraser, R.M., Kanoni, S., Kumar, A., Lagou, V., Langenberg, C., Luan, J., Lindgren, C.M., Müller-Nurasyid, M., Pechlivanis, S., Rayner, N.W., Scott, L.J., Wiltshire, S., Yengo, L., Kinnunen, L., Rossin, E.J., Raychaudhuri, S., Johnson, A.D., Dimas, A.S., Loos, R.J.F., Vedantam, S., Chen, H., Florez, J.C., Fox, C., Liu, C.-T., Rybin, D., Couper, D.J., Kao, W.H.L., Li, M., Cornelis, M.C., Kraft, P., Sun, Q., Van Dam, R.M., Stringham, H.M., Chines, P.S., Fischer, K., Fontanillas, P., Holmen, O.L., Hunt, S.E., Jackson, A.U., Kong, A., Lawrence, R., Meyer, J., Perry, J.R.B., Platou, C.G.P., Potter, S., Rehnberg, E., Robertson, N., Sivapalaratnam, S., Stančáková, A., Stirrups, K., Thorleifsson, G., Tikkanen, E., Wood, A.R., Almgren, P., Atalay, M., Benediktsson, R., Bonnycastle, L.L., Burtt, N., Carey, J., Charpentier, G., Crenshaw, A.T., Doney, A.S.F., Dorkhan, M., Edkins, S., Emilsson, V., Eury, E., Forsen, T., Gertow, K., Gigante, B., Grant, G.B., Groves, C.J., Guiducci, C., Herder, C., Hreidarsson, A.B., Hui, J., James, A., Jonsson, A., Rathmann, W., Klopp, N., Kravic, J., Krjutškov, K., Langford, C., Leander, K., Lindholm, E., Lobbens, S., MäNnistö, S., Mirza, G., MüHleisen, T.W., Musk, B., Parkin, M., Rallidis, L., Saramies, J., Sennblad, B., Shah, S., Sigursson, G., Silveira, A., Steinbach, G., Thorand, B., Trakalo, J., Veglia, F., Wennauer, R., Winckler, W., Zabaneh, D., Campbell, H., Van Duijn, C., Uitterlinden, A.G., Hofman, A., Sijbrands, E., Abecasis, G.R., Owen, K.R., Zeggini, E., Trip, M.D., Forouhi, N.G., Syvänen, A.-C., Eriksson, J.G., Peltonen, L., Nöthen, M.M., Balkau, B., Palmer, C.N.A., Lyssenko, V., Tuomi, T., Isomaa, B., Hunter, D.J., Qi, L., Shuldiner, A.R., Roden, M., Barroso, I., Wilsgaard, T., Beilby, J., Hovingh, K., Price, J.F., Wilson, J.F., Rauramaa, R., Lakka, T.A., Lind, L., Dedoussis, G., NjøLstad, I., Pedersen, N.L., Khaw, K.-T., Wareham, N.J., Keinanen-Kiukaanniemi, S.M., Saaristo, T.E., Korpi-HyöVäLti, E., Saltevo, J., Laakso, M., Kuusisto, J., Metspalu, A., Collins, F.S., Mohlke, K.L., Bergman, R.N., Tuomilehto, J., Boehm, B.O., Gieger, C., Hveem, K., Cauchi, S., Froguel, P., Baldassarre, D., Tremoli, E., Humphries, S.E., Saleheen, D., Danesh, J., Ingelsson, E., Ripatti, S., Salomaa, V., Erbel, R., JöCkel, K.-H., Moebus, S., Peters, A., Illig, T., Faire, U.D., Hamsten, A., Morris, A.D., Donnelly, P.J., Frayling, T.M., Hattersley, A.T., Boerwinkle, E., Melander, O., Kathiresan, S., Nilsson, P.M., Deloukas, P., Thorsteinsdottir, U., Groop, L.C., Stefansson, K., Hu, F., Pankow, J.S., Dupuis, J., Meigs, J.B., Altshuler, D., Boehnke, M., McCarthy, M.I. (2012-09). Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature Genetics 44 (9) : 981-990. ScholarBank@NUS Repository. https://doi.org/10.1038/ng.2383 10614036 http://scholarbank.nus.edu.sg/handle/10635/108768 000308491200009 Scopus |