Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

10.1039/c2ib20209c

Saved in:

Bibliographic Details
Main Authors:	Aref, A.R., Huang, R.Y.-J., Yu, W., Chua, K.-N., Sun, W., Tu, T.-Y., Bai, J., Sim, W.-J., Zervantonakis, I.K., Thiery, J.P., Kamm, R.D.
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Published:	2014
Online Access:	http://scholarbank.nus.edu.sg/handle/10635/110784
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

Similar Items

The EMT spectrum and therapeutic opportunities
by: Voon, D.C, et al.
Published: (2020)

Rapid microwell prototyping, generation of 3D multicellular cancer aggregates, and emt drug screening
by: Tu, T.-Y., et al.
Published: (2014)

Targeting pathways contributing to epithelial-mesenchymal transition (EMT) in epithelial ovarian cancer
by: Huang, R.Y.-J., et al.
Published: (2014)

Tumor dissemination: An EMT affair
by: Thiery, J.P., et al.
Published: (2014)

Alternative Path to EMT: Regulation of Apicobasal Polarity in Drosophila
by: Lim, J., et al.
Published: (2014)

Rapid prototyping of concave microwells for the formation of 3D multicellular cancer aggregates for drug screening
by: Tu, T.-Y., et al.
Published: (2014)

Engineering of In Vitro 3D Capillary Beds by Self-Directed Angiogenic Sprouting
by: Chan J.M., et al.
Published: (2019)

Functional relevance of a six mesenchymal gene signature in epithelial-mesenchymal transition (EMT) reversal by the triple angiokinase inhibitor, nintedanib (BIBF1120)
by: Huang, R.Y.-J, et al.
Published: (2020)

EMT-Induced Stemness and Tumorigenicity Are Fueled by the EGFR/Ras Pathway
by: Voon, D.C.-C., et al.
Published: (2014)

Snai1-driven sequential emt changes attributed by selective chromatin enrichment of RAD21 and GRHL2
by: Sundararajan, V., et al.
Published: (2021)

New insight towards development of paclitaxel and docetaxel resistance in cancer cells: EMT as a novel molecular mechanism and therapeutic possibilities
by: Ashrafizadeh, Milad, et al.
Published: (2022)

EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction
by: Akalay, I., et al.
Published: (2014)

An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)
by: Huang, R.Y.-J., et al.
Published: (2014)

ESTABLISHING AN EPITHELIAL MESENCHYMAL TRANSITION (EMT) SPECTRUM WITH EMT TRANSCRIPTIONAL DRIVERS
by: TAN MING
Published: (2017)

Association of the epithelial–mesenchymal transition (EMT) with cisplatin resistance
by: Ashrafizadeh, M., et al.
Published: (2021)

Unraveling the Molecular Nexus between GPCRs, ERS, and EMT
by: Niti Kumari, et al.
Published: (2022)

Complementary effects of ciclopirox olamine, a prolyl hydroxylase inhibitor and sphingosine 1-phosphate on fibroblasts and endothelial cells in driving capillary sprouting
by: Lim, S.H., et al.
Published: (2014)

Correction to: Sundararajan, v., et al. snai1-driven sequential emt changes attributed by selective chromatin enrichment of rad21 and grhl2. cancers 2020, 12, 1140
by: Sundararajan, V., et al.
Published: (2021)

Early events in cell adhesion and polarity during epithelialmesenchymal transition
by: Huang, R.Y.-J., et al.
Published: (2014)

Obstacles for T-lymphocytes in the tumour microenvironment: therapeutic challenges, advances and opportunities beyond immune checkpoint
by: Verma, Navin Kumar, et al.
Published: (2023)

Regulome of cancer epithelial-mesenchymal transition (EMT)
by: See, Benedict
Published: (2020)

The in situ light microenvironment of corals
by: Wangpraseurt, Daniel, et al.
Published: (2014)

A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer
by: Preca, B.-T, et al.
Published: (2020)

Stem Cells: Microenvironment, Micro/Nanotechnology, and Application
by: Liu H., et al.
Published: (2018)

A combined microfluidic-transcriptomic approach to characterize the extravasation potential of cancer cells
by: Bersini, S., et al.
Published: (2021)

Targeting metabolism in cancer cells and the tumour microenvironment for cancer therapy
by: Li, J., et al.
Published: (2021)

EV-out or EV-in: Tackling cell-to-cell communication within the tumor microenvironment to enhance anti-tumor efficacy using extracellular vesicle-based therapeutic strategies
by: Chiangjong W.
Published: (2023)

EHMT1/EHMT2 in EMT, cancer stemness and drug resistance: emerging evidence and mechanisms
by: Nachiyappan, A, et al.
Published: (2022)

Investigating the role of RUNX3 in Epithelial-Mesenchymal Transition (EMT).
by: Muhammad Bakhait Rahmat.
Published: (2013)

RUNX1 and RUNX3 protect against YAP-mediated EMT, stemness and shorter survival outcomes in breast cancer
by: Kulkarni, M, et al.
Published: (2020)

Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells
by: Bhattacharya, B., et al.
Published: (2022)

High throughput screening to investigate the interaction of stem cells with their extracellular microenvironment
by: Ankam, S., et al.
Published: (2014)

Ubiquitination and SUMOylation in the chronic inflammatory tumor microenvironment
by: Chang S.C., et al.
Published: (2019)

Hypoxia activated EGFR signaling induces epithelial to mesenchymal transition (EMT)
by: Misra, Ashish, et al.
Published: (2013)

The Roles of CD38 and CD157 in the Solid Tumor Microenvironment and Cancer Immunotherapy
by: Wo, Y.J., et al.
Published: (2021)

PDMS microdevice with built-in optical biosensor array for oil-site monitoring of the microenvironment within microchannels
by: Zhang, L., et al.
Published: (2014)

Inflammatory tumour microenvironment is associated with superior survival in hepatocellular carcinoma patients
by: Chew, V., et al.
Published: (2014)

DYNAMIC CHANGES IN 3D CHROMATIN STRUCTURE DURING EMT IN OVARIAN CANCER
by: PANG QING YOU
Published: (2020)

Quantitative screening of the effects of hyper-osmotic stress on cancer cells cultured in 2- or 3-dimensional settings
by: Miermont, A., et al.
Published: (2022)

Activation of STAT3 and STAT5 signaling in epithelial ovarian cancer progression: Mechanism and therapeutic opportunity
by: Wu, C.-J., et al.
Published: (2021)