Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases

10.1002/anie.201107833

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Main Authors: Woon, E.C.Y., Tumber, A., Kawamura, A., Hillringhaus, L., Ge, W., Rose, N.R., Ma, J.H.Y., Chan, M.C., Walport, L.J., Che, K.H., Ng, S.S., Marsden, B.D., Oppermann, U., McDonough, M.A., Schofield, C.J.
Other Authors: PHARMACY
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Published: 2016
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Online Access:http://scholarbank.nus.edu.sg/handle/10635/125025
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spelling sg-nus-scholar.10635-1250252023-10-25T21:50:28Z Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases Woon, E.C.Y. Tumber, A. Kawamura, A. Hillringhaus, L. Ge, W. Rose, N.R. Ma, J.H.Y. Chan, M.C. Walport, L.J. Che, K.H. Ng, S.S. Marsden, B.D. Oppermann, U. McDonough, M.A. Schofield, C.J. PHARMACY 2-oxoglutarate epigenetics histone lysine demethylases oxygenases thiol-ene reaction 10.1002/anie.201107833 Angewandte Chemie - International Edition 51 7 1631-1634 ACIEF 2016-06-02T10:29:56Z 2016-06-02T10:29:56Z 2012-02-13 Article Woon, E.C.Y., Tumber, A., Kawamura, A., Hillringhaus, L., Ge, W., Rose, N.R., Ma, J.H.Y., Chan, M.C., Walport, L.J., Che, K.H., Ng, S.S., Marsden, B.D., Oppermann, U., McDonough, M.A., Schofield, C.J. (2012-02-13). Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases. Angewandte Chemie - International Edition 51 (7) : 1631-1634. ScholarBank@NUS Repository. https://doi.org/10.1002/anie.201107833 14337851 http://scholarbank.nus.edu.sg/handle/10635/125025 000299946400023 Scopus
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic 2-oxoglutarate
epigenetics
histone lysine demethylases
oxygenases
thiol-ene reaction
spellingShingle 2-oxoglutarate
epigenetics
histone lysine demethylases
oxygenases
thiol-ene reaction
Woon, E.C.Y.
Tumber, A.
Kawamura, A.
Hillringhaus, L.
Ge, W.
Rose, N.R.
Ma, J.H.Y.
Chan, M.C.
Walport, L.J.
Che, K.H.
Ng, S.S.
Marsden, B.D.
Oppermann, U.
McDonough, M.A.
Schofield, C.J.
Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases
description 10.1002/anie.201107833
author2 PHARMACY
author_facet PHARMACY
Woon, E.C.Y.
Tumber, A.
Kawamura, A.
Hillringhaus, L.
Ge, W.
Rose, N.R.
Ma, J.H.Y.
Chan, M.C.
Walport, L.J.
Che, K.H.
Ng, S.S.
Marsden, B.D.
Oppermann, U.
McDonough, M.A.
Schofield, C.J.
format Article
author Woon, E.C.Y.
Tumber, A.
Kawamura, A.
Hillringhaus, L.
Ge, W.
Rose, N.R.
Ma, J.H.Y.
Chan, M.C.
Walport, L.J.
Che, K.H.
Ng, S.S.
Marsden, B.D.
Oppermann, U.
McDonough, M.A.
Schofield, C.J.
author_sort Woon, E.C.Y.
title Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases
title_short Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases
title_full Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases
title_fullStr Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases
title_full_unstemmed Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases
title_sort linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of jmjc histone demethylases
publishDate 2016
url http://scholarbank.nus.edu.sg/handle/10635/125025
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