Action of YM155 on clear cell renal cell carcinoma does not depend on surviving expression levels

10.1371/journal.pone.0178168

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Main Authors:	Sim M.Y., Huynh H., Go M.L., Yuen J.S.P.
Other Authors:	PHARMACOLOGY
Format:	Article
Published:	2019
Subjects:	inhibitor of differentiation 1 messenger RNA sepantronium bromide sorafenib survivin transcription factor FKHR von Hippel Lindau protein antineoplastic agent BIRC5 protein, human carbanilamide derivative CYLD protein, human drug combination FOXO1 protein, human ID1 protein, human imidazole derivative inhibitor of apoptosis protein naphthoquinone nicotinamide tumor suppressor protein VHL protein, human animal experiment animal model animal tissue Article BIRC5 gene cancer inhibition cell viability controlled study CYLD gene drug dose comparison drug potentiation FOXO1 gene gene gene expression human human cell ID1 gene in vivo study kidney carcinoma male microarray analysis mouse nonhuman protein expression real time polymerase chain reaction renal cell carcinoma cell line transcriptomics tumor regression tumor xenograft Western blotting analogs and derivatives animal antagonists and inhibitors Carcinoma, Renal Cell cell survival dose response drug effects drug screening gene expression regulation genetics Kidney Neoplasms metabolism pathology primary cell culture SCID mouse signal transduction tumor cell line Animals Antineoplastic Agents Cell Line, Tumor Cell Survival Dose-Response Relationship, Drug Drug Combinations Forkhead Box Protein O1 Gene Expression Regulation, Neoplastic Humans Imidazoles Inhibitor of Apoptosis Proteins Inhibitor of Differentiation Protein 1 Male Mice Mice, SCID Naphthoquinones Niacinamide Phenylurea Compounds Primary Cell Culture Signal Transduction Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Xenograft Model Antitumor Assays
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161190
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1611902024-04-05T09:04:00Z Action of YM155 on clear cell renal cell carcinoma does not depend on surviving expression levels Sim M.Y. Huynh H. Go M.L. Yuen J.S.P. PHARMACOLOGY PHARMACY DUKE-NUS MEDICAL SCHOOL inhibitor of differentiation 1 messenger RNA sepantronium bromide sorafenib survivin transcription factor FKHR von Hippel Lindau protein antineoplastic agent BIRC5 protein, human carbanilamide derivative CYLD protein, human drug combination FOXO1 protein, human ID1 protein, human imidazole derivative inhibitor of apoptosis protein inhibitor of differentiation 1 naphthoquinone nicotinamide sepantronium bromide sorafenib transcription factor FKHR tumor suppressor protein VHL protein, human von Hippel Lindau protein animal experiment animal model animal tissue Article BIRC5 gene cancer inhibition cell viability controlled study CYLD gene drug dose comparison drug potentiation FOXO1 gene gene gene expression human human cell ID1 gene in vivo study kidney carcinoma male microarray analysis mouse nonhuman protein expression real time polymerase chain reaction renal cell carcinoma cell line transcriptomics tumor regression tumor xenograft Western blotting analogs and derivatives animal antagonists and inhibitors Carcinoma, Renal Cell cell survival dose response drug combination drug effects drug screening gene expression regulation genetics Kidney Neoplasms metabolism pathology primary cell culture SCID mouse signal transduction tumor cell line Animals Antineoplastic Agents Carcinoma, Renal Cell Cell Line, Tumor Cell Survival Dose-Response Relationship, Drug Drug Combinations Forkhead Box Protein O1 Gene Expression Regulation, Neoplastic Humans Imidazoles Inhibitor of Apoptosis Proteins Inhibitor of Differentiation Protein 1 Kidney Neoplasms Male Mice Mice, SCID Naphthoquinones Niacinamide Phenylurea Compounds Primary Cell Culture Signal Transduction Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Xenograft Model Antitumor Assays 10.1371/journal.pone.0178168 PLoS ONE 12 6 e0178168 2019-11-01T07:52:18Z 2019-11-01T07:52:18Z 2017 Article Sim M.Y., Huynh H., Go M.L., Yuen J.S.P. (2017). Action of YM155 on clear cell renal cell carcinoma does not depend on surviving expression levels. PLoS ONE 12 (6) : e0178168. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0178168 19326203 https://scholarbank.nus.edu.sg/handle/10635/161190 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	inhibitor of differentiation 1 messenger RNA sepantronium bromide sorafenib survivin transcription factor FKHR von Hippel Lindau protein antineoplastic agent BIRC5 protein, human carbanilamide derivative CYLD protein, human drug combination FOXO1 protein, human ID1 protein, human imidazole derivative inhibitor of apoptosis protein inhibitor of differentiation 1 naphthoquinone nicotinamide sepantronium bromide sorafenib transcription factor FKHR tumor suppressor protein VHL protein, human von Hippel Lindau protein animal experiment animal model animal tissue Article BIRC5 gene cancer inhibition cell viability controlled study CYLD gene drug dose comparison drug potentiation FOXO1 gene gene gene expression human human cell ID1 gene in vivo study kidney carcinoma male microarray analysis mouse nonhuman protein expression real time polymerase chain reaction renal cell carcinoma cell line transcriptomics tumor regression tumor xenograft Western blotting analogs and derivatives animal antagonists and inhibitors Carcinoma, Renal Cell cell survival dose response drug combination drug effects drug screening gene expression regulation genetics Kidney Neoplasms metabolism pathology primary cell culture SCID mouse signal transduction tumor cell line Animals Antineoplastic Agents Carcinoma, Renal Cell Cell Line, Tumor Cell Survival Dose-Response Relationship, Drug Drug Combinations Forkhead Box Protein O1 Gene Expression Regulation, Neoplastic Humans Imidazoles Inhibitor of Apoptosis Proteins Inhibitor of Differentiation Protein 1 Kidney Neoplasms Male Mice Mice, SCID Naphthoquinones Niacinamide Phenylurea Compounds Primary Cell Culture Signal Transduction Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Xenograft Model Antitumor Assays
spellingShingle	inhibitor of differentiation 1 messenger RNA sepantronium bromide sorafenib survivin transcription factor FKHR von Hippel Lindau protein antineoplastic agent BIRC5 protein, human carbanilamide derivative CYLD protein, human drug combination FOXO1 protein, human ID1 protein, human imidazole derivative inhibitor of apoptosis protein inhibitor of differentiation 1 naphthoquinone nicotinamide sepantronium bromide sorafenib transcription factor FKHR tumor suppressor protein VHL protein, human von Hippel Lindau protein animal experiment animal model animal tissue Article BIRC5 gene cancer inhibition cell viability controlled study CYLD gene drug dose comparison drug potentiation FOXO1 gene gene gene expression human human cell ID1 gene in vivo study kidney carcinoma male microarray analysis mouse nonhuman protein expression real time polymerase chain reaction renal cell carcinoma cell line transcriptomics tumor regression tumor xenograft Western blotting analogs and derivatives animal antagonists and inhibitors Carcinoma, Renal Cell cell survival dose response drug combination drug effects drug screening gene expression regulation genetics Kidney Neoplasms metabolism pathology primary cell culture SCID mouse signal transduction tumor cell line Animals Antineoplastic Agents Carcinoma, Renal Cell Cell Line, Tumor Cell Survival Dose-Response Relationship, Drug Drug Combinations Forkhead Box Protein O1 Gene Expression Regulation, Neoplastic Humans Imidazoles Inhibitor of Apoptosis Proteins Inhibitor of Differentiation Protein 1 Kidney Neoplasms Male Mice Mice, SCID Naphthoquinones Niacinamide Phenylurea Compounds Primary Cell Culture Signal Transduction Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Xenograft Model Antitumor Assays Sim M.Y. Huynh H. Go M.L. Yuen J.S.P. Action of YM155 on clear cell renal cell carcinoma does not depend on surviving expression levels
description	10.1371/journal.pone.0178168
author2	PHARMACOLOGY
author_facet	PHARMACOLOGY Sim M.Y. Huynh H. Go M.L. Yuen J.S.P.
format	Article
author	Sim M.Y. Huynh H. Go M.L. Yuen J.S.P.
author_sort	Sim M.Y.
title	Action of YM155 on clear cell renal cell carcinoma does not depend on surviving expression levels
title_short	Action of YM155 on clear cell renal cell carcinoma does not depend on surviving expression levels
title_full	Action of YM155 on clear cell renal cell carcinoma does not depend on surviving expression levels
title_fullStr	Action of YM155 on clear cell renal cell carcinoma does not depend on surviving expression levels
title_full_unstemmed	Action of YM155 on clear cell renal cell carcinoma does not depend on surviving expression levels
title_sort	action of ym155 on clear cell renal cell carcinoma does not depend on surviving expression levels
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161190
_version_	1800913782266920960

Action of YM155 on clear cell renal cell carcinoma does not depend on surviving expression levels

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