Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects

10.1371/journal.pone.0089397

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Bibliographic Details
Main Authors:	Bard-Chapeau E.A., Szumska D., Jacob B., Chua B.Q.L., Chatterjee G.C., Zhang Y., Ward J.M., Urun F., Kinameri E., Vincent S.D., Ahmed S., Bhattacharya S., Osato M., Perkins A.S., Moore A.W., Jenkins N.A., Copeland N.G.
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Published:	2019
Subjects:	adult allele amino terminal sequence animal cell animal experiment animal model animal tissue article binding site congenital heart malformation controlled study disease severity embryo embryo development EVI1 gene exon gene deletion gene function gene identification gene location gene silencing gene targeting germ line hematopoietic cell heterozygote lethality mouse newborn nonhuman perinatal period phenotype regulator gene transcription initiation site Alleles Animals Animals, Newborn Base Sequence Bone Marrow Disease Models, Animal DNA-Binding Proteins Exons Gene Deletion Gene Expression Regulation, Developmental Genes, Lethal Genetic Association Studies Heart Defects, Congenital Hematopoiesis Hematopoietic Stem Cells Immunophenotyping Mice Mice, Knockout Molecular Sequence Data Mutation Phenotype Proto-Oncogenes Sequence Alignment Severity of Illness Index Transcription Factors
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161427
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Institution:	National University of Singapore

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