Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-Thrombomodulin fusion with endogenous cofactor

• Main Authors: Greineder C.F., Chacko A.-M., Zaytsev S., Zern B.J., Carnemolla R., Hood E.D., Han J., Ding B.-S., Esmon C.T., Muzykantov V.R.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: Acute Lung Injury; Animals; Antigens, CD; Antigens, CD31; Cell Line; Endothelial Cells; Endothelium, Vascular; Humans; Immunoconjugates; Intercellular Adhesion Molecule-1; Intercellular Junctions; Male; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Protein C; Receptors, Cell Surface; Single-Chain Antibodies; Thrombomodulin
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161455
• Institution: National University of Singapore

10.1371/journal.pone.0080110