Complexation and Sequestration of BMP-2 from an ECM Mimetic Hyaluronan Gel for Improved Bone Formation
10.1371/journal.pone.0078551
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sg-nus-scholar.10635-1614592024-04-18T06:55:36Z Complexation and Sequestration of BMP-2 from an ECM Mimetic Hyaluronan Gel for Improved Bone Formation Kisiel M. Klar A.S. Ventura M. Buijs J. Mafina M.-K. Cool S.M. Hilborn J. ORTHOPAEDIC SURGERY alkaline phosphatase bone morphogenetic protein 2 dermatan sulfate glycosaminoglycan heparin hyaluronic acid Bmp2 protein, rat bone morphogenetic protein 2 hyaluronic acid immobilized protein immunological adjuvant angiogenesis animal experiment animal model article assay binding affinity binding kinetics biological activity bone mass bone mineral bone structure complex formation controlled study covalent bond enzyme activity extracellular matrix histology immunohistochemistry in vitro study in vivo study male micro-computed tomography nonhuman ossification protein metabolism protein secretion protein stability rat scanning electron microscopy surface plasmon resonance animal bone development cell culture chemistry drug effects human Sprague Dawley rat time Adjuvants, Immunologic Animals Bone Morphogenetic Protein 2 Cells, Cultured Humans Hyaluronic Acid Immobilized Proteins Male Osteogenesis Rats Rats, Sprague-Dawley Time Factors 10.1371/journal.pone.0078551 PLoS ONE 8 10 e78551 2019-11-05T02:11:17Z 2019-11-05T02:11:17Z 2013 Article Kisiel M., Klar A.S., Ventura M., Buijs J., Mafina M.-K., Cool S.M., Hilborn J. (2013). Complexation and Sequestration of BMP-2 from an ECM Mimetic Hyaluronan Gel for Improved Bone Formation. PLoS ONE 8 (10) : e78551. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0078551 1932-6203 https://scholarbank.nus.edu.sg/handle/10635/161459 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101 |
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alkaline phosphatase bone morphogenetic protein 2 dermatan sulfate glycosaminoglycan heparin hyaluronic acid Bmp2 protein, rat bone morphogenetic protein 2 hyaluronic acid immobilized protein immunological adjuvant angiogenesis animal experiment animal model article assay binding affinity binding kinetics biological activity bone mass bone mineral bone structure complex formation controlled study covalent bond enzyme activity extracellular matrix histology immunohistochemistry in vitro study in vivo study male micro-computed tomography nonhuman ossification protein metabolism protein secretion protein stability rat scanning electron microscopy surface plasmon resonance animal bone development cell culture chemistry drug effects human Sprague Dawley rat time Adjuvants, Immunologic Animals Bone Morphogenetic Protein 2 Cells, Cultured Humans Hyaluronic Acid Immobilized Proteins Male Osteogenesis Rats Rats, Sprague-Dawley Time Factors |
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alkaline phosphatase bone morphogenetic protein 2 dermatan sulfate glycosaminoglycan heparin hyaluronic acid Bmp2 protein, rat bone morphogenetic protein 2 hyaluronic acid immobilized protein immunological adjuvant angiogenesis animal experiment animal model article assay binding affinity binding kinetics biological activity bone mass bone mineral bone structure complex formation controlled study covalent bond enzyme activity extracellular matrix histology immunohistochemistry in vitro study in vivo study male micro-computed tomography nonhuman ossification protein metabolism protein secretion protein stability rat scanning electron microscopy surface plasmon resonance animal bone development cell culture chemistry drug effects human Sprague Dawley rat time Adjuvants, Immunologic Animals Bone Morphogenetic Protein 2 Cells, Cultured Humans Hyaluronic Acid Immobilized Proteins Male Osteogenesis Rats Rats, Sprague-Dawley Time Factors Kisiel M. Klar A.S. Ventura M. Buijs J. Mafina M.-K. Cool S.M. Hilborn J. Complexation and Sequestration of BMP-2 from an ECM Mimetic Hyaluronan Gel for Improved Bone Formation |
| description |
10.1371/journal.pone.0078551 |
| author2 |
ORTHOPAEDIC SURGERY |
| author_facet |
ORTHOPAEDIC SURGERY Kisiel M. Klar A.S. Ventura M. Buijs J. Mafina M.-K. Cool S.M. Hilborn J. |
| format |
Article |
| author |
Kisiel M. Klar A.S. Ventura M. Buijs J. Mafina M.-K. Cool S.M. Hilborn J. |
| author_sort |
Kisiel M. |
| title |
Complexation and Sequestration of BMP-2 from an ECM Mimetic Hyaluronan Gel for Improved Bone Formation |
| title_short |
Complexation and Sequestration of BMP-2 from an ECM Mimetic Hyaluronan Gel for Improved Bone Formation |
| title_full |
Complexation and Sequestration of BMP-2 from an ECM Mimetic Hyaluronan Gel for Improved Bone Formation |
| title_fullStr |
Complexation and Sequestration of BMP-2 from an ECM Mimetic Hyaluronan Gel for Improved Bone Formation |
| title_full_unstemmed |
Complexation and Sequestration of BMP-2 from an ECM Mimetic Hyaluronan Gel for Improved Bone Formation |
| title_sort |
complexation and sequestration of bmp-2 from an ecm mimetic hyaluronan gel for improved bone formation |
| publishDate |
2019 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/161459 |
| _version_ |
1800913795656187904 |