Melatonin suppresses toll like receptor 4-dependent caspase-3 signaling activation coupled with reduced production of proinflammatory mediators in Hypoxic Microgli?

10.1371/journal.pone.0166010

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Main Authors:	Yao L., Lu P., Ling E.-A.
Other Authors:	ANATOMY
Format:	Article
Published:	2019
Subjects:	caspase 3 inducible nitric oxide synthase interleukin 1beta melatonin messenger RNA toll like receptor 4 transcription factor RelA tumor necrosis factor autacoid animal cell animal experiment animal model animal tissue antiinflammatory activity Article brain hypoxia cell hypoxia controlled study in vitro study microglia newborn newborn hypoxia nonhuman protein expression rat animal cytology deficiency drug effects enzyme activation gene expression regulation gene silencing genetics metabolism signal transduction Wistar rat Animals Caspase 3 Cell Hypoxia Enzyme Activation Gene Expression Regulation Gene Knockdown Techniques Inflammation Mediators Melatonin Microglia Rats Rats, Wistar Signal Transduction Toll-Like Receptor 4
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161546
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1615462024-04-08T14:25:55Z Melatonin suppresses toll like receptor 4-dependent caspase-3 signaling activation coupled with reduced production of proinflammatory mediators in Hypoxic Microgli? Yao L. Lu P. Ling E.-A. ANATOMY caspase 3 inducible nitric oxide synthase interleukin 1beta melatonin messenger RNA toll like receptor 4 transcription factor RelA tumor necrosis factor autacoid caspase 3 melatonin toll like receptor 4 animal cell animal experiment animal model animal tissue antiinflammatory activity Article brain hypoxia cell hypoxia controlled study in vitro study microglia newborn newborn hypoxia nonhuman protein expression rat animal cytology deficiency drug effects enzyme activation gene expression regulation gene silencing genetics metabolism microglia signal transduction Wistar rat Animals Caspase 3 Cell Hypoxia Enzyme Activation Gene Expression Regulation Gene Knockdown Techniques Inflammation Mediators Melatonin Microglia Rats Rats, Wistar Signal Transduction Toll-Like Receptor 4 10.1371/journal.pone.0166010 PLoS ONE 11 11 e0166010 2019-11-06T07:45:02Z 2019-11-06T07:45:02Z 2016 Article Yao L., Lu P., Ling E.-A. (2016). Melatonin suppresses toll like receptor 4-dependent caspase-3 signaling activation coupled with reduced production of proinflammatory mediators in Hypoxic Microgli?. PLoS ONE 11 (11) : e0166010. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0166010 19326203 https://scholarbank.nus.edu.sg/handle/10635/161546 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	caspase 3 inducible nitric oxide synthase interleukin 1beta melatonin messenger RNA toll like receptor 4 transcription factor RelA tumor necrosis factor autacoid caspase 3 melatonin toll like receptor 4 animal cell animal experiment animal model animal tissue antiinflammatory activity Article brain hypoxia cell hypoxia controlled study in vitro study microglia newborn newborn hypoxia nonhuman protein expression rat animal cytology deficiency drug effects enzyme activation gene expression regulation gene silencing genetics metabolism microglia signal transduction Wistar rat Animals Caspase 3 Cell Hypoxia Enzyme Activation Gene Expression Regulation Gene Knockdown Techniques Inflammation Mediators Melatonin Microglia Rats Rats, Wistar Signal Transduction Toll-Like Receptor 4
spellingShingle	caspase 3 inducible nitric oxide synthase interleukin 1beta melatonin messenger RNA toll like receptor 4 transcription factor RelA tumor necrosis factor autacoid caspase 3 melatonin toll like receptor 4 animal cell animal experiment animal model animal tissue antiinflammatory activity Article brain hypoxia cell hypoxia controlled study in vitro study microglia newborn newborn hypoxia nonhuman protein expression rat animal cytology deficiency drug effects enzyme activation gene expression regulation gene silencing genetics metabolism microglia signal transduction Wistar rat Animals Caspase 3 Cell Hypoxia Enzyme Activation Gene Expression Regulation Gene Knockdown Techniques Inflammation Mediators Melatonin Microglia Rats Rats, Wistar Signal Transduction Toll-Like Receptor 4 Yao L. Lu P. Ling E.-A. Melatonin suppresses toll like receptor 4-dependent caspase-3 signaling activation coupled with reduced production of proinflammatory mediators in Hypoxic Microgli?
description	10.1371/journal.pone.0166010
author2	ANATOMY
author_facet	ANATOMY Yao L. Lu P. Ling E.-A.
format	Article
author	Yao L. Lu P. Ling E.-A.
author_sort	Yao L.
title	Melatonin suppresses toll like receptor 4-dependent caspase-3 signaling activation coupled with reduced production of proinflammatory mediators in Hypoxic Microgli?
title_short	Melatonin suppresses toll like receptor 4-dependent caspase-3 signaling activation coupled with reduced production of proinflammatory mediators in Hypoxic Microgli?
title_full	Melatonin suppresses toll like receptor 4-dependent caspase-3 signaling activation coupled with reduced production of proinflammatory mediators in Hypoxic Microgli?
title_fullStr	Melatonin suppresses toll like receptor 4-dependent caspase-3 signaling activation coupled with reduced production of proinflammatory mediators in Hypoxic Microgli?
title_full_unstemmed	Melatonin suppresses toll like receptor 4-dependent caspase-3 signaling activation coupled with reduced production of proinflammatory mediators in Hypoxic Microgli?
title_sort	melatonin suppresses toll like receptor 4-dependent caspase-3 signaling activation coupled with reduced production of proinflammatory mediators in hypoxic microgli?
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161546
_version_	1800913799255949312

Melatonin suppresses toll like receptor 4-dependent caspase-3 signaling activation coupled with reduced production of proinflammatory mediators in Hypoxic Microgli?

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