Locked nucleic acid probe-based real-time PCR assay for the rapid detection of rifampin-resistant Mycobacterium tuberculosis

10.1371/journal.pone.0143444

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Main Authors:	Zhao Y., Li G., Sun C., Li C., Wang X., Liu H., Zhang P., Zhao X., Jiang Y., Yang R., Wan K., Zhou L.
Other Authors:	MEDICINE
Format:	Article
Published:	2019
Subjects:	rifampicin bacterial protein DNA directed RNA polymerase DNA probe locked nucleic acid oligonucleotide rpoB protein, Mycobacterium tuberculosis Article bacterial gene bacterial strain bacterium detection bacterium isolate codon controlled study diagnostic value DNA sequence drug resistance drug resistant tuberculosis limit of detection locked nucleic acid probe based real time polymerase chain reaction molecular probe multiplex polymerase chain reaction mutational analysis Mycobacterium tuberculosis nonhuman quantitative analysis real time polymerase chain reaction rpoB gene sensitivity and specificity sequence analysis validation process antibiotic resistance drug effects genetics human microbiology mutation procedures reproducibility Tuberculosis, Multidrug-Resistant Bacterial Proteins DNA Probes DNA-Directed RNA Polymerases Drug Resistance, Bacterial Humans Multiplex Polymerase Chain Reaction Mutation Oligonucleotides Real-Time Polymerase Chain Reaction Reproducibility of Results Rifampin Sensitivity and Specificity
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161603
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1616032024-04-24T05:53:39Z Locked nucleic acid probe-based real-time PCR assay for the rapid detection of rifampin-resistant Mycobacterium tuberculosis Zhao Y. Li G. Sun C. Li C. Wang X. Liu H. Zhang P. Zhao X. Wang X. Jiang Y. Yang R. Wan K. Zhou L. MEDICINE rifampicin bacterial protein DNA directed RNA polymerase DNA probe locked nucleic acid oligonucleotide rifampicin rpoB protein, Mycobacterium tuberculosis Article bacterial gene bacterial strain bacterium detection bacterium isolate codon controlled study diagnostic value DNA sequence drug resistance drug resistant tuberculosis limit of detection locked nucleic acid probe based real time polymerase chain reaction molecular probe multiplex polymerase chain reaction mutational analysis Mycobacterium tuberculosis nonhuman quantitative analysis real time polymerase chain reaction rpoB gene sensitivity and specificity sequence analysis validation process antibiotic resistance DNA probe drug effects genetics human microbiology mutation Mycobacterium tuberculosis procedures real time polymerase chain reaction reproducibility Tuberculosis, Multidrug-Resistant Bacterial Proteins DNA Probes DNA-Directed RNA Polymerases Drug Resistance, Bacterial Humans Multiplex Polymerase Chain Reaction Mutation Mycobacterium tuberculosis Oligonucleotides Real-Time Polymerase Chain Reaction Reproducibility of Results Rifampin Sensitivity and Specificity Tuberculosis, Multidrug-Resistant 10.1371/journal.pone.0143444 PLoS ONE 10 11 e0143444 2019-11-06T08:07:43Z 2019-11-06T08:07:43Z 2015 Article Zhao Y., Li G., Sun C., Li C., Wang X., Liu H., Zhang P., Zhao X., Wang X., Jiang Y., Yang R., Wan K., Zhou L. (2015). Locked nucleic acid probe-based real-time PCR assay for the rapid detection of rifampin-resistant Mycobacterium tuberculosis. PLoS ONE 10 (11) : e0143444. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0143444 19326203 https://scholarbank.nus.edu.sg/handle/10635/161603 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	rifampicin bacterial protein DNA directed RNA polymerase DNA probe locked nucleic acid oligonucleotide rifampicin rpoB protein, Mycobacterium tuberculosis Article bacterial gene bacterial strain bacterium detection bacterium isolate codon controlled study diagnostic value DNA sequence drug resistance drug resistant tuberculosis limit of detection locked nucleic acid probe based real time polymerase chain reaction molecular probe multiplex polymerase chain reaction mutational analysis Mycobacterium tuberculosis nonhuman quantitative analysis real time polymerase chain reaction rpoB gene sensitivity and specificity sequence analysis validation process antibiotic resistance DNA probe drug effects genetics human microbiology mutation Mycobacterium tuberculosis procedures real time polymerase chain reaction reproducibility Tuberculosis, Multidrug-Resistant Bacterial Proteins DNA Probes DNA-Directed RNA Polymerases Drug Resistance, Bacterial Humans Multiplex Polymerase Chain Reaction Mutation Mycobacterium tuberculosis Oligonucleotides Real-Time Polymerase Chain Reaction Reproducibility of Results Rifampin Sensitivity and Specificity Tuberculosis, Multidrug-Resistant
spellingShingle	rifampicin bacterial protein DNA directed RNA polymerase DNA probe locked nucleic acid oligonucleotide rifampicin rpoB protein, Mycobacterium tuberculosis Article bacterial gene bacterial strain bacterium detection bacterium isolate codon controlled study diagnostic value DNA sequence drug resistance drug resistant tuberculosis limit of detection locked nucleic acid probe based real time polymerase chain reaction molecular probe multiplex polymerase chain reaction mutational analysis Mycobacterium tuberculosis nonhuman quantitative analysis real time polymerase chain reaction rpoB gene sensitivity and specificity sequence analysis validation process antibiotic resistance DNA probe drug effects genetics human microbiology mutation Mycobacterium tuberculosis procedures real time polymerase chain reaction reproducibility Tuberculosis, Multidrug-Resistant Bacterial Proteins DNA Probes DNA-Directed RNA Polymerases Drug Resistance, Bacterial Humans Multiplex Polymerase Chain Reaction Mutation Mycobacterium tuberculosis Oligonucleotides Real-Time Polymerase Chain Reaction Reproducibility of Results Rifampin Sensitivity and Specificity Tuberculosis, Multidrug-Resistant Zhao Y. Li G. Sun C. Li C. Wang X. Liu H. Zhang P. Zhao X. Wang X. Jiang Y. Yang R. Wan K. Zhou L. Locked nucleic acid probe-based real-time PCR assay for the rapid detection of rifampin-resistant Mycobacterium tuberculosis
description	10.1371/journal.pone.0143444
author2	MEDICINE
author_facet	MEDICINE Zhao Y. Li G. Sun C. Li C. Wang X. Liu H. Zhang P. Zhao X. Wang X. Jiang Y. Yang R. Wan K. Zhou L.
format	Article
author	Zhao Y. Li G. Sun C. Li C. Wang X. Liu H. Zhang P. Zhao X. Wang X. Jiang Y. Yang R. Wan K. Zhou L.
author_sort	Zhao Y.
title	Locked nucleic acid probe-based real-time PCR assay for the rapid detection of rifampin-resistant Mycobacterium tuberculosis
title_short	Locked nucleic acid probe-based real-time PCR assay for the rapid detection of rifampin-resistant Mycobacterium tuberculosis
title_full	Locked nucleic acid probe-based real-time PCR assay for the rapid detection of rifampin-resistant Mycobacterium tuberculosis
title_fullStr	Locked nucleic acid probe-based real-time PCR assay for the rapid detection of rifampin-resistant Mycobacterium tuberculosis
title_full_unstemmed	Locked nucleic acid probe-based real-time PCR assay for the rapid detection of rifampin-resistant Mycobacterium tuberculosis
title_sort	locked nucleic acid probe-based real-time pcr assay for the rapid detection of rifampin-resistant mycobacterium tuberculosis
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161603
_version_	1800913802577838080

Locked nucleic acid probe-based real-time PCR assay for the rapid detection of rifampin-resistant Mycobacterium tuberculosis

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