Crystal structure of the Dengue virus methyltransferase bound to a 5?-capped octameric RNA

• Main Authors: Yap L.J., Luo D., Chung K.Y., Lim S.P., Bodenreider C., Noble C., Shi P.-Y., Lescar J.
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Format: Article
• Published: 2019
• Subjects: adenine; capped RNA; cytosine; guanine; methyltransferase; monomer; protein DENV 3; unclassified drug; virus RNA; virus protein; 5' untranslated region; article; base pairing; crystal structure; crystallography; Dengue virus; enzyme defect; enzyme structure; nonhuman; protein methylation; protein RNA binding; RNA stability; RNA structure; structure analysis; virus genome; amino acid sequence; binding site; chemical structure; chemistry; conformation; enzymology; genetics; metabolism; molecular genetics; protein binding; protein tertiary structure; X ray crystallography; Flavivirus; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Dengue Virus; Methyltransferases; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Protein Binding; Protein Structure, Tertiary; RNA Caps; RNA, Viral; Viral Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161807
• Institution: National University of Singapore

10.1371/journal.pone.0012836