Polymorphisms in MTHFR, MS and CBS genes and homocysteine levels in a Pakistani population

• Main Authors: Yakub M., Moti N., Parveen S., Chaudhry B., Azam I., Iqbal M.P.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: 5,10 methylenetetrahydrofolate reductase (FADH2); cyanocobalamin; cystathionine beta synthase; folic acid; homocysteine; lead; methionine synthase; pyridoxal 5 phosphate; 5 methyltetrahydrofolate homocysteine methyltransferase; methylenetetrahydrofolate reductase (NADPH2); adult; amino acid blood level; article; blood sampling; CBS gene; controlled study; cross-sectional study; cyanocobalamin deficiency; DNA isolation; DNA polymorphism; environmental factor; female; folic acid blood level; folic acid deficiency; gene; gene function; gene interaction; genetic analysis; genetic risk; genetic variability; genotype; heterozygosity; homozygosity; human; human experiment; hyperhomocysteinemia; lead blood level; lowest income group; male; MS gene; mthfr gene; normal human; Pakistan; restriction fragment length polymorphism; urban population; venous blood; vitamin blood level; adolescent; blood; genetics; heterozygote; homozygote; middle aged; risk; risk factor; sex difference; single nucleotide polymorphism; 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Pyridoxal Phosphate; Risk Factors; Sex Factors; Vitamin B 12; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161994
• Institution: National University of Singapore

10.1371/journal.pone.0033222