Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B

10.1371/journal.pone.0028177

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Main Authors:	Lim T.-P., Lee W., Tan T.-Y., Sasikala S., Teo J., Hsu L.-Y., Tan T.-T., Syahidah N., Kwa A.L.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2019
Subjects:	amikacin levofloxacin meropenem metallo beta lactamase polymyxin B rifampicin antiinfective agent beta lactamase ofloxacin thienamycin derivative antibiotic sensitivity article bacterial count bacterial strain bactericidal activity bacterium isolate colony forming unit genotype immunocompromised patient in vitro study minimum inhibitory concentration nonhuman phenotype phylogeny polymerase chain reaction Pseudomonas aeruginosa Pseudomonas infection public hospital Singapore antibiotic resistance drug combination drug potentiation human metabolism methodology microbiological examination time Amikacin Anti-Bacterial Agents beta-Lactamases Drug Resistance, Bacterial Drug Synergism Drug Therapy, Combination Humans Microbial Sensitivity Tests Ofloxacin Phylogeny Polymyxin B Pseudomonas Infections Rifampin Thienamycins Time Factors
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/162021
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-162021
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spelling	sg-nus-scholar.10635-1620212021-02-19T09:37:57Z Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B Lim T.-P. Lee W. Tan T.-Y. Sasikala S. Teo J. Hsu L.-Y. Tan T.-T. Syahidah N. Kwa A.L. DUKE-NUS MEDICAL SCHOOL SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) amikacin levofloxacin meropenem metallo beta lactamase polymyxin B rifampicin amikacin antiinfective agent beta lactamase meropenem ofloxacin polymyxin B rifampicin thienamycin derivative antibiotic sensitivity article bacterial count bacterial strain bactericidal activity bacterium isolate colony forming unit genotype immunocompromised patient in vitro study minimum inhibitory concentration nonhuman phenotype phylogeny polymerase chain reaction Pseudomonas aeruginosa Pseudomonas infection public hospital Singapore antibiotic resistance drug combination drug potentiation human metabolism methodology microbiological examination Pseudomonas infection time Amikacin Anti-Bacterial Agents beta-Lactamases Drug Resistance, Bacterial Drug Synergism Drug Therapy, Combination Humans Microbial Sensitivity Tests Ofloxacin Phylogeny Polymyxin B Pseudomonas aeruginosa Pseudomonas Infections Rifampin Thienamycins Time Factors 10.1371/journal.pone.0028177 PLoS ONE 6 12 e28177 2019-11-11T08:36:06Z 2019-11-11T08:36:06Z 2011 Article Lim T.-P., Lee W., Tan T.-Y., Sasikala S., Teo J., Hsu L.-Y., Tan T.-T., Syahidah N., Kwa A.L. (2011). Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B. PLoS ONE 6 (12) : e28177. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0028177 19326203 https://scholarbank.nus.edu.sg/handle/10635/162021 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	amikacin levofloxacin meropenem metallo beta lactamase polymyxin B rifampicin amikacin antiinfective agent beta lactamase meropenem ofloxacin polymyxin B rifampicin thienamycin derivative antibiotic sensitivity article bacterial count bacterial strain bactericidal activity bacterium isolate colony forming unit genotype immunocompromised patient in vitro study minimum inhibitory concentration nonhuman phenotype phylogeny polymerase chain reaction Pseudomonas aeruginosa Pseudomonas infection public hospital Singapore antibiotic resistance drug combination drug potentiation human metabolism methodology microbiological examination Pseudomonas infection time Amikacin Anti-Bacterial Agents beta-Lactamases Drug Resistance, Bacterial Drug Synergism Drug Therapy, Combination Humans Microbial Sensitivity Tests Ofloxacin Phylogeny Polymyxin B Pseudomonas aeruginosa Pseudomonas Infections Rifampin Thienamycins Time Factors
spellingShingle	amikacin levofloxacin meropenem metallo beta lactamase polymyxin B rifampicin amikacin antiinfective agent beta lactamase meropenem ofloxacin polymyxin B rifampicin thienamycin derivative antibiotic sensitivity article bacterial count bacterial strain bactericidal activity bacterium isolate colony forming unit genotype immunocompromised patient in vitro study minimum inhibitory concentration nonhuman phenotype phylogeny polymerase chain reaction Pseudomonas aeruginosa Pseudomonas infection public hospital Singapore antibiotic resistance drug combination drug potentiation human metabolism methodology microbiological examination Pseudomonas infection time Amikacin Anti-Bacterial Agents beta-Lactamases Drug Resistance, Bacterial Drug Synergism Drug Therapy, Combination Humans Microbial Sensitivity Tests Ofloxacin Phylogeny Polymyxin B Pseudomonas aeruginosa Pseudomonas Infections Rifampin Thienamycins Time Factors Lim T.-P. Lee W. Tan T.-Y. Sasikala S. Teo J. Hsu L.-Y. Tan T.-T. Syahidah N. Kwa A.L. Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B
description	10.1371/journal.pone.0028177
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Lim T.-P. Lee W. Tan T.-Y. Sasikala S. Teo J. Hsu L.-Y. Tan T.-T. Syahidah N. Kwa A.L.
format	Article
author	Lim T.-P. Lee W. Tan T.-Y. Sasikala S. Teo J. Hsu L.-Y. Tan T.-T. Syahidah N. Kwa A.L.
author_sort	Lim T.-P.
title	Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B
title_short	Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B
title_full	Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B
title_fullStr	Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B
title_full_unstemmed	Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B
title_sort	effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin b
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/162021
_version_	1693115948273238016

Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B

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