Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B

• Main Authors: Lim T.-P., Lee W., Tan T.-Y., Sasikala S., Teo J., Hsu L.-Y., Tan T.-T., Syahidah N., Kwa A.L.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: amikacin; levofloxacin; meropenem; metallo beta lactamase; polymyxin B; rifampicin; antiinfective agent; beta lactamase; ofloxacin; thienamycin derivative; antibiotic sensitivity; article; bacterial count; bacterial strain; bactericidal activity; bacterium isolate; colony forming unit; genotype; immunocompromised patient; in vitro study; minimum inhibitory concentration; nonhuman; phenotype; phylogeny; polymerase chain reaction; Pseudomonas aeruginosa; Pseudomonas infection; public hospital; Singapore; antibiotic resistance; drug combination; drug potentiation; human; metabolism; methodology; microbiological examination; time; Amikacin; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Ofloxacin; Phylogeny; Polymyxin B; Pseudomonas Infections; Rifampin; Thienamycins; Time Factors
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/162021
• Institution: National University of Singapore

10.1371/journal.pone.0028177