Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B

Effective antibiotics in combination against extreme drug-resistant pseudomonas aeruginosa with decreased susceptibility to polymyxin B

10.1371/journal.pone.0028177

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Bibliographic Details
Main Authors:	Lim T.-P., Lee W., Tan T.-Y., Sasikala S., Teo J., Hsu L.-Y., Tan T.-T., Syahidah N., Kwa A.L.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2019
Subjects:	amikacin levofloxacin meropenem metallo beta lactamase polymyxin B rifampicin antiinfective agent beta lactamase ofloxacin thienamycin derivative antibiotic sensitivity article bacterial count bacterial strain bactericidal activity bacterium isolate colony forming unit genotype immunocompromised patient in vitro study minimum inhibitory concentration nonhuman phenotype phylogeny polymerase chain reaction Pseudomonas aeruginosa Pseudomonas infection public hospital Singapore antibiotic resistance drug combination drug potentiation human metabolism methodology microbiological examination time Amikacin Anti-Bacterial Agents beta-Lactamases Drug Resistance, Bacterial Drug Synergism Drug Therapy, Combination Humans Microbial Sensitivity Tests Ofloxacin Phylogeny Polymyxin B Pseudomonas Infections Rifampin Thienamycins Time Factors
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/162021
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Institution:	National University of Singapore

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