CYP5122A1, a novel cytochrome P450 is essential for survival of Leishmania donovani

CYP5122A1, a novel cytochrome P450 is essential for survival of Leishmania donovani

10.1371/journal.pone.0025273

Saved in:

Bibliographic Details
Main Authors:	Verma S., Mehta A., Shaha C.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2019
Subjects:	amphotericin B antimony calcium ion cytochrome P450 cytochrome P450 5122A1 ergosterol miltefosine neomycin unclassified drug adenosine triphosphate protozoal protein reactive oxygen metabolite allele article controlled study endoplasmic reticulum enzyme activity enzyme localization glycosome hamster in vitro study in vivo study Leishmania donovani macrophage mass fragmentography membrane potential mitochondrion nonhuman parasite survival phenotype promastigote protein expression wild type animal classification drug effect genetics genome immunohistochemistry metabolism parasitology pathogenicity phylogeny polyacrylamide gel electrophoresis Syrian hamster visceral leishmaniasis Western blotting Cricetinae Adenosine Triphosphate Animals Blotting, Western Cytochrome P-450 Enzyme System Electrophoresis, Polyacrylamide Gel Ergosterol Genome, Protozoan Immunohistochemistry Leishmaniasis, Visceral Mesocricetus Mitochondria Phylogeny Protozoan Proteins Reactive Oxygen Species
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/162031
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

Be the first to leave a comment!