Probiotics modulate intestinal expression of nuclear receptor and provide Counter-Regulatory signals to Inflammation-Driven adipose tissue activation

Probiotics modulate intestinal expression of nuclear receptor and provide Counter-Regulatory signals to Inflammation-Driven adipose tissue activation

10.1371/journal.pone.0022978

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Bibliographic Details
Main Authors:	Mencarelli A., Distrutti E., Renga B., D'Amore C., Cipriani S., Palladino G., Donini A., Ricci P., Fiorucci S.
Other Authors:	DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
Format:	Article
Published:	2019
Subjects:	adiponectin cell nucleus receptor ciprofloxacin farnesoid X receptor gamma interferon interleukin 6 leptin liver X receptor metronidazole peroxisome proliferator activated receptor alpha peroxisome proliferator activated receptor gamma pregnane X receptor probiotic agent tumor necrosis factor alpha tumor necrosis factor alpha inhibitor VSL3 cell receptor cytokine farnesoid X-activated receptor messenger RNA orphan nuclear receptor steroid receptor trinitrobenzenesulfonic acid abdominal abscess abdominal fat adipose tissue adult animal experiment animal model animal tissue antiinflammatory activity article clinical article clinical feature colitis colon cancer concentration response controlled study Crohn disease disease course enteritis enzyme activation female human human tissue immunomodulation inflammation intestine cell intestine fistula male mouse nonhuman protein expression protein function protein localization protein secretion regulatory mechanism signal transduction tissue culture tissue level treatment duration animal cell culture chemically induced disorder drug effect enzyme immunoassay enzyme linked immunosorbent assay genetic transcription genetics intestine mesentery metabolism pathology pathophysiology reverse transcription polymerase chain reaction Western blotting Animalia Mus Rodentia Adipose Tissue Adult Animals Blotting, Western Cells, Cultured Colitis Cytokines Enzyme-Linked Immunosorbent Assay Female Humans Immunoenzyme Techniques Inflammation Intestines Male Mesentery Mice Orphan Nuclear Receptors PPAR gamma Probiotics Receptors, Cytoplasmic and Nuclear Receptors, Steroid Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger Signal Transduction Transcription, Genetic Trinitrobenzenesulfonic Acid
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/162037
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Institution:	National University of Singapore

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