The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology

10.1371/journal.ppat.1002504

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Main Authors:	Hafalla J.C.R., Claser C., Couper K.N., Grau G.E., Renia L., de Souza J.B., Riley E.M.
Other Authors:	MICROBIOLOGY AND IMMUNOLOGY
Format:	Article
Published:	Public Library of Science 2020
Subjects:	cytotoxic T lymphocyte antigen 4 gamma interferon programmed death 1 ligand 1 Cd274 protein, mouse differentiation antigen PD 1 antigen, mouse PD-1 antigen, mouse animal cell animal experiment animal model animal tissue article Bagg albino mouse brain malaria C57BL 6 mouse CD8+ T lymphocyte controlled study homeostasis host resistance immune response lymphocyte depletion mouse nonhuman Plasmodium berghei infection protein expression T lymphocyte activation animal C57BL mouse erythrocyte immunology lymphocyte activation malaria metabolism microbiology parasitology pathogenicity pathology Plasmodium berghei Mus Animals Antigens, CD274 Antigens, Differentiation CD8-Positive T-Lymphocytes CTLA-4 Antigen Erythrocytes Interferon-gamma Lymphocyte Activation Malaria, Cerebral Mice Mice, Inbred BALB C Mice, Inbred C57BL
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165409
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1654092024-03-27T08:19:09Z The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology Hafalla J.C.R. Claser C. Couper K.N. Grau G.E. Renia L. de Souza J.B. Riley E.M. MICROBIOLOGY AND IMMUNOLOGY cytotoxic T lymphocyte antigen 4 gamma interferon programmed death 1 ligand 1 Cd274 protein, mouse cytotoxic T lymphocyte antigen 4 differentiation antigen gamma interferon PD 1 antigen, mouse PD-1 antigen, mouse programmed death 1 ligand 1 animal cell animal experiment animal model animal tissue article Bagg albino mouse brain malaria C57BL 6 mouse CD8+ T lymphocyte controlled study homeostasis host resistance immune response lymphocyte depletion mouse nonhuman Plasmodium berghei infection protein expression T lymphocyte activation animal C57BL mouse CD8+ T lymphocyte erythrocyte immunology lymphocyte activation malaria metabolism microbiology parasitology pathogenicity pathology Plasmodium berghei Mus Plasmodium berghei Animals Antigens, CD274 Antigens, Differentiation CD8-Positive T-Lymphocytes CTLA-4 Antigen Erythrocytes Interferon-gamma Lymphocyte Activation Malaria, Cerebral Mice Mice, Inbred BALB C Mice, Inbred C57BL Plasmodium berghei 10.1371/journal.ppat.1002504 PLoS Pathogens 8 2 e1002504 2020-03-13T05:26:14Z 2020-03-13T05:26:14Z 2012 Article Hafalla J.C.R., Claser C., Couper K.N., Grau G.E., Renia L., de Souza J.B., Riley E.M. (2012). The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS Pathogens 8 (2) : e1002504. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.ppat.1002504 15537366 https://scholarbank.nus.edu.sg/handle/10635/165409 Public Library of Science Unpaywall 20200320
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	cytotoxic T lymphocyte antigen 4 gamma interferon programmed death 1 ligand 1 Cd274 protein, mouse cytotoxic T lymphocyte antigen 4 differentiation antigen gamma interferon PD 1 antigen, mouse PD-1 antigen, mouse programmed death 1 ligand 1 animal cell animal experiment animal model animal tissue article Bagg albino mouse brain malaria C57BL 6 mouse CD8+ T lymphocyte controlled study homeostasis host resistance immune response lymphocyte depletion mouse nonhuman Plasmodium berghei infection protein expression T lymphocyte activation animal C57BL mouse CD8+ T lymphocyte erythrocyte immunology lymphocyte activation malaria metabolism microbiology parasitology pathogenicity pathology Plasmodium berghei Mus Plasmodium berghei Animals Antigens, CD274 Antigens, Differentiation CD8-Positive T-Lymphocytes CTLA-4 Antigen Erythrocytes Interferon-gamma Lymphocyte Activation Malaria, Cerebral Mice Mice, Inbred BALB C Mice, Inbred C57BL Plasmodium berghei
spellingShingle	cytotoxic T lymphocyte antigen 4 gamma interferon programmed death 1 ligand 1 Cd274 protein, mouse cytotoxic T lymphocyte antigen 4 differentiation antigen gamma interferon PD 1 antigen, mouse PD-1 antigen, mouse programmed death 1 ligand 1 animal cell animal experiment animal model animal tissue article Bagg albino mouse brain malaria C57BL 6 mouse CD8+ T lymphocyte controlled study homeostasis host resistance immune response lymphocyte depletion mouse nonhuman Plasmodium berghei infection protein expression T lymphocyte activation animal C57BL mouse CD8+ T lymphocyte erythrocyte immunology lymphocyte activation malaria metabolism microbiology parasitology pathogenicity pathology Plasmodium berghei Mus Plasmodium berghei Animals Antigens, CD274 Antigens, Differentiation CD8-Positive T-Lymphocytes CTLA-4 Antigen Erythrocytes Interferon-gamma Lymphocyte Activation Malaria, Cerebral Mice Mice, Inbred BALB C Mice, Inbred C57BL Plasmodium berghei Hafalla J.C.R. Claser C. Couper K.N. Grau G.E. Renia L. de Souza J.B. Riley E.M. The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology
description	10.1371/journal.ppat.1002504
author2	MICROBIOLOGY AND IMMUNOLOGY
author_facet	MICROBIOLOGY AND IMMUNOLOGY Hafalla J.C.R. Claser C. Couper K.N. Grau G.E. Renia L. de Souza J.B. Riley E.M.
format	Article
author	Hafalla J.C.R. Claser C. Couper K.N. Grau G.E. Renia L. de Souza J.B. Riley E.M.
author_sort	Hafalla J.C.R.
title	The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology
title_short	The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology
title_full	The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology
title_fullStr	The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology
title_full_unstemmed	The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology
title_sort	ctla-4 and pd-1/pd-l1 inhibitory pathways independently regulate host resistance to plasmodium-induced acute immune pathology
publisher	Public Library of Science
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/165409
_version_	1795300820031373312

The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology

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