Host resistance to Plasmodium-induced acute immune pathology is regulated by interleukin- 10 receptor signaling

• Main Authors: Claser, C, De Souza, J.B, Thorburn, S.G, Grau, G.E, Riley, E.M, Rénia, L, Hafalla, J.C.R
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: American Society for Microbiology 2020
• Subjects: CD3 antigen; CD4 antigen; CD8 antigen; gamma interferon; interleukin 10; interleukin 10 receptor; L selectin; lymphocyte function associated antigen 1; blocking antibody; neutralizing antibody; animal cell; animal experiment; animal model; animal tissue; Article; brain histology; CD8+ T lymphocyte; cerebral malaria; controlled study; erythrocyte; female; host resistance; immune response; immunopathology; immunoregulation; incidence; lethality; mouse; nonhuman; parasitemia; pathogen clearance; Plasmodium; Plasmodium berghei infection; priority journal; signal transduction; T lymphocyte activation; tissue injury; animal; antagonists and inhibitors; Bagg albino mouse; blood; brain; C57BL mouse; drug effects; immunology; liver; lymphocyte activation; parasitology; pathology; Plasmodium berghei; Animals; Antibodies, Blocking; Antibodies, Neutralizing; Brain; CD8-Positive T-Lymphocytes; Erythrocytes; Female; Interferon-gamma; Liver; Lymphocyte Activation; Malaria, Cerebral; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Parasitemia; Receptors, Interleukin-10; Signal Transduction
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179200
• Institution: National University of Singapore

10.1128/IAI.00941-16