Cd8+ T cells and IFN-? mediate the time-dependent accumulation of infected red blood cells in deep organs during experimental cerebral malaria

10.1371/journal.pone.0018720

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Bibliographic Details
Main Authors:	Claser C., Malleret B., Gun S.Y., Wong A.Y.W., Chang Z.W., Teo P., See P.C.E., Howland S.W., Ginhoux F., Rénia L.
Other Authors:	MICROBIOLOGY AND IMMUNOLOGY
Format:	Article
Published:	2019
Subjects:	gamma interferon interleukin 12 luciferase tumor necrosis factor alpha DNA binding protein Rag2 protein, mouse animal cell animal experiment animal model animal tissue article bioaccumulation brain malaria CD4+ T lymphocyte CD8+ T lymphocyte cell selection cell subpopulation cellular distribution diagnostic imaging disease course erythrocyte ex vivo study female in vivo study male microbial biomass monocyte mouse neutrophil nonhuman organ pathogenesis Plasmodium berghei Plasmodium berghei infection protein expression time lapse imaging animal antibody specificity biomass bone marrow cell brain C57BL mouse immunology lymphocyte depletion malaria metabolism parasitology pathology physiology time Mus Animals Biomass Brain CD8-Positive T-Lymphocytes DNA-Binding Proteins Erythrocytes Female Interferon-gamma Lymphocyte Depletion Malaria, Cerebral Male Mice Mice, Inbred C57BL Myeloid Cells Organ Specificity Time Factors
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161795
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Institution:	National University of Singapore

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