Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-o-methyltransferase nsp10/nsp16 complex
10.1371/journal.ppat.1002059
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2020
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sg-nus-scholar.10635-1654122023-11-01T07:32:24Z Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-o-methyltransferase nsp10/nsp16 complex Decroly E. Debarnot C. Ferron F. Bouvet M. Coutard B. Imbert I. Gluais L. Papageorgiou N. Sharff A. Bricogne G. Ortiz-Lombardia M. Lescar J. Canard B. DUKE-NUS MEDICAL SCHOOL methyltransferase RNA s adenosylmethionine SARS coronavirus RNA Cap 2' o methyltransferase nsp10 nsp16 complex sinefungin unclassified drug adenosine capped RNA drug derivative magnesium Nsp10 protein, SARS virus Nsp16 protein, SARS virus rna 2' o methyltransferase RNA 2'-O-methyltransferase virus protein virus RNA article binding site catalysis crystal structure crystallization enzyme activity nonhuman protein analysis protein binding protein protein interaction protein structure RNA binding RNA capping SARS coronavirus chemistry genetics metabolism mutation plasmid RNA viruses SARS coronavirus Adenosine Crystallization Magnesium Methyltransferases Mutation Plasmids Protein Binding RNA Caps RNA, Viral S-Adenosylmethionine SARS Virus Viral Nonstructural Proteins 10.1371/journal.ppat.1002059 PLoS Pathogens 7 5 e1002059 2020-03-13T05:26:34Z 2020-03-13T05:26:34Z 2011 Article Decroly E., Debarnot C., Ferron F., Bouvet M., Coutard B., Imbert I., Gluais L., Papageorgiou N., Sharff A., Bricogne G., Ortiz-Lombardia M., Lescar J., Canard B. (2011). Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-o-methyltransferase nsp10/nsp16 complex. PLoS Pathogens 7 (5) : e1002059. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.ppat.1002059 15537366 https://scholarbank.nus.edu.sg/handle/10635/165412 Public Library of Science Unpaywall 20200320 |
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methyltransferase RNA s adenosylmethionine SARS coronavirus RNA Cap 2' o methyltransferase nsp10 nsp16 complex sinefungin unclassified drug adenosine capped RNA drug derivative magnesium Nsp10 protein, SARS virus Nsp16 protein, SARS virus rna 2' o methyltransferase RNA 2'-O-methyltransferase virus protein virus RNA article binding site catalysis crystal structure crystallization enzyme activity nonhuman protein analysis protein binding protein protein interaction protein structure RNA binding RNA capping SARS coronavirus chemistry genetics metabolism mutation plasmid RNA viruses SARS coronavirus Adenosine Crystallization Magnesium Methyltransferases Mutation Plasmids Protein Binding RNA Caps RNA, Viral S-Adenosylmethionine SARS Virus Viral Nonstructural Proteins |
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methyltransferase RNA s adenosylmethionine SARS coronavirus RNA Cap 2' o methyltransferase nsp10 nsp16 complex sinefungin unclassified drug adenosine capped RNA drug derivative magnesium Nsp10 protein, SARS virus Nsp16 protein, SARS virus rna 2' o methyltransferase RNA 2'-O-methyltransferase virus protein virus RNA article binding site catalysis crystal structure crystallization enzyme activity nonhuman protein analysis protein binding protein protein interaction protein structure RNA binding RNA capping SARS coronavirus chemistry genetics metabolism mutation plasmid RNA viruses SARS coronavirus Adenosine Crystallization Magnesium Methyltransferases Mutation Plasmids Protein Binding RNA Caps RNA, Viral S-Adenosylmethionine SARS Virus Viral Nonstructural Proteins Decroly E. Debarnot C. Ferron F. Bouvet M. Coutard B. Imbert I. Gluais L. Papageorgiou N. Sharff A. Bricogne G. Ortiz-Lombardia M. Lescar J. Canard B. Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-o-methyltransferase nsp10/nsp16 complex |
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10.1371/journal.ppat.1002059 |
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DUKE-NUS MEDICAL SCHOOL |
author_facet |
DUKE-NUS MEDICAL SCHOOL Decroly E. Debarnot C. Ferron F. Bouvet M. Coutard B. Imbert I. Gluais L. Papageorgiou N. Sharff A. Bricogne G. Ortiz-Lombardia M. Lescar J. Canard B. |
format |
Article |
author |
Decroly E. Debarnot C. Ferron F. Bouvet M. Coutard B. Imbert I. Gluais L. Papageorgiou N. Sharff A. Bricogne G. Ortiz-Lombardia M. Lescar J. Canard B. |
author_sort |
Decroly E. |
title |
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-o-methyltransferase nsp10/nsp16 complex |
title_short |
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-o-methyltransferase nsp10/nsp16 complex |
title_full |
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-o-methyltransferase nsp10/nsp16 complex |
title_fullStr |
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-o-methyltransferase nsp10/nsp16 complex |
title_full_unstemmed |
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-o-methyltransferase nsp10/nsp16 complex |
title_sort |
crystal structure and functional analysis of the sars-coronavirus rna cap 2′-o-methyltransferase nsp10/nsp16 complex |
publisher |
Public Library of Science |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/165412 |
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1781791936325091328 |