Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites

10.1371/journal.ppat.1000104

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Main Authors: Gao X., Yeo K.P., Aw S.S., Kuss C., Iyer J.K., Genesan S., Rajamanonmani R., Lescar J., Bozdech Z., Preiser P.R.
Other Authors: DUKE-NUS MEDICAL SCHOOL
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Published: Public Library of Science 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/165424
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spelling sg-nus-scholar.10635-1654242024-11-14T04:05:04Z Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites Gao X. Yeo K.P. Aw S.S. Kuss C. Iyer J.K. Genesan S. Rajamanonmani R. Lescar J. Bozdech Z. Preiser P.R. DUKE-NUS MEDICAL SCHOOL antibody binding protein protein protein pfrh1 cell adhesion molecule cell surface receptor Duffy antigen binding protein, Plasmodium parasite antigen protozoal protein protozoon antibody recombinant protein RH1 protein, Plasmodium falciparum animal cell article controlled study merozoite multigene family nonhuman parasite virulence Plasmodium falciparum protein analysis protein domain protein expression animal binding site blood cell strain COS1 Cercopithecus chemistry circular dichroism erythrocyte gene expression regulation gene silencing host parasite interaction immunology merozoite metabolism parasitology pathogenicity physiology Plasmodium falciparum Animals Antibodies, Protozoan Antigens, Protozoan Binding Sites Cell Adhesion Molecules Cercopithecus aethiops Circular Dichroism COS Cells Erythrocytes Gene Expression Regulation Gene Silencing Host-Parasite Interactions Merozoites Plasmodium falciparum Protozoan Proteins Receptors, Cell Surface Recombinant Proteins 10.1371/journal.ppat.1000104 PLoS Pathogens 4 7 e1000104 2020-03-13T05:27:55Z 2020-03-13T05:27:55Z 2008 Article Gao X., Yeo K.P., Aw S.S., Kuss C., Iyer J.K., Genesan S., Rajamanonmani R., Lescar J., Bozdech Z., Preiser P.R. (2008). Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites. PLoS Pathogens 4 (7) : e1000104. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.ppat.1000104 15537366 https://scholarbank.nus.edu.sg/handle/10635/165424 Public Library of Science Unpaywall 20200320
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic antibody
binding protein
protein
protein pfrh1
cell adhesion molecule
cell surface receptor
Duffy antigen binding protein, Plasmodium
parasite antigen
protozoal protein
protozoon antibody
recombinant protein
RH1 protein, Plasmodium falciparum
animal cell
article
controlled study
merozoite
multigene family
nonhuman
parasite virulence
Plasmodium falciparum
protein analysis
protein domain
protein expression
animal
binding site
blood
cell strain COS1
Cercopithecus
chemistry
circular dichroism
erythrocyte
gene expression regulation
gene silencing
host parasite interaction
immunology
merozoite
metabolism
parasitology
pathogenicity
physiology
Plasmodium falciparum
Animals
Antibodies, Protozoan
Antigens, Protozoan
Binding Sites
Cell Adhesion Molecules
Cercopithecus aethiops
Circular Dichroism
COS Cells
Erythrocytes
Gene Expression Regulation
Gene Silencing
Host-Parasite Interactions
Merozoites
Plasmodium falciparum
Protozoan Proteins
Receptors, Cell Surface
Recombinant Proteins
spellingShingle antibody
binding protein
protein
protein pfrh1
cell adhesion molecule
cell surface receptor
Duffy antigen binding protein, Plasmodium
parasite antigen
protozoal protein
protozoon antibody
recombinant protein
RH1 protein, Plasmodium falciparum
animal cell
article
controlled study
merozoite
multigene family
nonhuman
parasite virulence
Plasmodium falciparum
protein analysis
protein domain
protein expression
animal
binding site
blood
cell strain COS1
Cercopithecus
chemistry
circular dichroism
erythrocyte
gene expression regulation
gene silencing
host parasite interaction
immunology
merozoite
metabolism
parasitology
pathogenicity
physiology
Plasmodium falciparum
Animals
Antibodies, Protozoan
Antigens, Protozoan
Binding Sites
Cell Adhesion Molecules
Cercopithecus aethiops
Circular Dichroism
COS Cells
Erythrocytes
Gene Expression Regulation
Gene Silencing
Host-Parasite Interactions
Merozoites
Plasmodium falciparum
Protozoan Proteins
Receptors, Cell Surface
Recombinant Proteins
Gao X.
Yeo K.P.
Aw S.S.
Kuss C.
Iyer J.K.
Genesan S.
Rajamanonmani R.
Lescar J.
Bozdech Z.
Preiser P.R.
Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites
description 10.1371/journal.ppat.1000104
author2 DUKE-NUS MEDICAL SCHOOL
author_facet DUKE-NUS MEDICAL SCHOOL
Gao X.
Yeo K.P.
Aw S.S.
Kuss C.
Iyer J.K.
Genesan S.
Rajamanonmani R.
Lescar J.
Bozdech Z.
Preiser P.R.
format Article
author Gao X.
Yeo K.P.
Aw S.S.
Kuss C.
Iyer J.K.
Genesan S.
Rajamanonmani R.
Lescar J.
Bozdech Z.
Preiser P.R.
author_sort Gao X.
title Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites
title_short Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites
title_full Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites
title_fullStr Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites
title_full_unstemmed Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites
title_sort antibodies targeting the pfrh1 binding domain inhibit invasion of plasmodium falciparum merozoites
publisher Public Library of Science
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/165424
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