Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites
10.1371/journal.ppat.1000104
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sg-nus-scholar.10635-1654242024-11-14T04:05:04Z Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites Gao X. Yeo K.P. Aw S.S. Kuss C. Iyer J.K. Genesan S. Rajamanonmani R. Lescar J. Bozdech Z. Preiser P.R. DUKE-NUS MEDICAL SCHOOL antibody binding protein protein protein pfrh1 cell adhesion molecule cell surface receptor Duffy antigen binding protein, Plasmodium parasite antigen protozoal protein protozoon antibody recombinant protein RH1 protein, Plasmodium falciparum animal cell article controlled study merozoite multigene family nonhuman parasite virulence Plasmodium falciparum protein analysis protein domain protein expression animal binding site blood cell strain COS1 Cercopithecus chemistry circular dichroism erythrocyte gene expression regulation gene silencing host parasite interaction immunology merozoite metabolism parasitology pathogenicity physiology Plasmodium falciparum Animals Antibodies, Protozoan Antigens, Protozoan Binding Sites Cell Adhesion Molecules Cercopithecus aethiops Circular Dichroism COS Cells Erythrocytes Gene Expression Regulation Gene Silencing Host-Parasite Interactions Merozoites Plasmodium falciparum Protozoan Proteins Receptors, Cell Surface Recombinant Proteins 10.1371/journal.ppat.1000104 PLoS Pathogens 4 7 e1000104 2020-03-13T05:27:55Z 2020-03-13T05:27:55Z 2008 Article Gao X., Yeo K.P., Aw S.S., Kuss C., Iyer J.K., Genesan S., Rajamanonmani R., Lescar J., Bozdech Z., Preiser P.R. (2008). Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites. PLoS Pathogens 4 (7) : e1000104. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.ppat.1000104 15537366 https://scholarbank.nus.edu.sg/handle/10635/165424 Public Library of Science Unpaywall 20200320 |
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antibody binding protein protein protein pfrh1 cell adhesion molecule cell surface receptor Duffy antigen binding protein, Plasmodium parasite antigen protozoal protein protozoon antibody recombinant protein RH1 protein, Plasmodium falciparum animal cell article controlled study merozoite multigene family nonhuman parasite virulence Plasmodium falciparum protein analysis protein domain protein expression animal binding site blood cell strain COS1 Cercopithecus chemistry circular dichroism erythrocyte gene expression regulation gene silencing host parasite interaction immunology merozoite metabolism parasitology pathogenicity physiology Plasmodium falciparum Animals Antibodies, Protozoan Antigens, Protozoan Binding Sites Cell Adhesion Molecules Cercopithecus aethiops Circular Dichroism COS Cells Erythrocytes Gene Expression Regulation Gene Silencing Host-Parasite Interactions Merozoites Plasmodium falciparum Protozoan Proteins Receptors, Cell Surface Recombinant Proteins |
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antibody binding protein protein protein pfrh1 cell adhesion molecule cell surface receptor Duffy antigen binding protein, Plasmodium parasite antigen protozoal protein protozoon antibody recombinant protein RH1 protein, Plasmodium falciparum animal cell article controlled study merozoite multigene family nonhuman parasite virulence Plasmodium falciparum protein analysis protein domain protein expression animal binding site blood cell strain COS1 Cercopithecus chemistry circular dichroism erythrocyte gene expression regulation gene silencing host parasite interaction immunology merozoite metabolism parasitology pathogenicity physiology Plasmodium falciparum Animals Antibodies, Protozoan Antigens, Protozoan Binding Sites Cell Adhesion Molecules Cercopithecus aethiops Circular Dichroism COS Cells Erythrocytes Gene Expression Regulation Gene Silencing Host-Parasite Interactions Merozoites Plasmodium falciparum Protozoan Proteins Receptors, Cell Surface Recombinant Proteins Gao X. Yeo K.P. Aw S.S. Kuss C. Iyer J.K. Genesan S. Rajamanonmani R. Lescar J. Bozdech Z. Preiser P.R. Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites |
description |
10.1371/journal.ppat.1000104 |
author2 |
DUKE-NUS MEDICAL SCHOOL |
author_facet |
DUKE-NUS MEDICAL SCHOOL Gao X. Yeo K.P. Aw S.S. Kuss C. Iyer J.K. Genesan S. Rajamanonmani R. Lescar J. Bozdech Z. Preiser P.R. |
format |
Article |
author |
Gao X. Yeo K.P. Aw S.S. Kuss C. Iyer J.K. Genesan S. Rajamanonmani R. Lescar J. Bozdech Z. Preiser P.R. |
author_sort |
Gao X. |
title |
Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites |
title_short |
Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites |
title_full |
Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites |
title_fullStr |
Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites |
title_full_unstemmed |
Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites |
title_sort |
antibodies targeting the pfrh1 binding domain inhibit invasion of plasmodium falciparum merozoites |
publisher |
Public Library of Science |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/165424 |
_version_ |
1821198231871160320 |